Human Serpin F2/alpha 2-Antiplasmin DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Serpin F2/alpha 2-Antiplasmin DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: SERPINF2

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 degreesC. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Serpin F2/alpha 2-Antiplasmin DuoSet ELISA, 5 Plate

• AAPclade F (alpha-2 antiplasmin
• alpha 2-Antiplasmin
• Alpha-2-AP
• Alpha-2-PI
• Alpha-2-plasmin inhibitor
• pigment epithelium derived factor), member 2
• Serpin F2
• serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epitheliumderived factor), member 2

Background

The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.

Publications for Serpin F2/alpha 2-Antiplasmin (DY1470-05)(1)

Publication using DY1470-05

• S Viganò, G D'Andrea, PD Valle, R Santacroce, M Margaglion, A D'Angelo A novel allele variant of the SERPINF2 gene responsible for severe plasmin inhibitor (α2-antiplasmin) deficiency in an Italian patient Thromb. Res., 2018-04-07;166(0):60-62. 2018-04-07 [PMID: 29656168] (Human)

Bioinformatics

• Gene Symbol: SERPINF2