Human Serpin E1/PAI-1 DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Human Serpin E1/PAI-1 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
SERPINE1

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY1786.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Serpin E1/PAI-1 DuoSet ELISA, 15 Plate

  • Endothelial plasminogen activator inhibitor
  • Nexin
  • PAI1
  • PAI-1
  • PAI1PAI-1
  • PAISerpin E1
  • PLANH1
  • PLANH1plasminogen activator inhibitor 1
  • serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogenactivator inhibitor type 1), member 1
  • Serpin E1
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitortype 1), member 1

Background

The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.

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Publications for Serpin E1/PAI-1 (DY1786)(10)

We have publications tested in 1 confirmed species: Human.


Filter By Application
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Human
(10)
All Species
Showing Publications 1 - 10 of 10.
Publications using DY1786 Applications Species
MR Hadjichara, BT Roux, E Csomor, CA Feghali-Bo, LA Murray, DL Clarke, MA Lindsay Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis Sci Rep, 2019;9(1):6020. 2019 [PMID: 30988425] (Human) Human
RS Thwaites, NC Gunawardan, V Broich, EH Mann, J Ahnström, GA Campbell, S Lindsley, N Singh, T Tunstall, DA Lane, PJ Openshaw, CM Hawrylowic, TT Hansel Biphasic activation of complement and fibrinolysis during the human nasal allergic response J. Allergy Clin. Immunol., 2018;0(0):. 2018 [PMID: 29427640] (Human) Human
M Ossorio, MA Bajo, G Del Peso, V Martínez, M Fernández, MJ Castro, A Rodríguez-, R Madero, T Bellón, R Selgas Sustained low peritoneal effluent CCL18 levels are associated with preservation of peritoneal membrane function in peritoneal dialysis PLoS ONE, 2017;12(4):e0175835. 2017 [PMID: 28414753] (Human) Human
CA Valle Oseg, JV Spencer Human cytomegalovirus interleukin-10 enhances matrigel invasion of MDA-MB-231 breast cancer cells Cancer Cell Int, 2017;17(0):24. 2017 [PMID: 28228690] (Human) Human
Serum from Varicose Patients Induces Senescence-Related Dysfunction of Vascular Endothelium Generating Local and Systemic Proinflammatory Conditions Oxid Med Cell Longev, 2016;2016(0):2069290. 2016 [PMID: 27994710] (Human) Human
Aubin K, Safoine M, Proulx M, Audet-Casgrain M, Côté J, Tetu F, Roy A, Fradette J Characterization of In Vitro Engineered Human Adipose Tissues: Relevant Adipokine Secretion and Impact of TNF-alpha. PLoS ONE, 2015;10(9):e0137612. 2015 [PMID: 26367137] (Human) Human
Tasev D, van Wijhe M, Weijers E, van Hinsbergh V, Koolwijk P Long-Term Expansion in Platelet Lysate Increases Growth of Peripheral Blood-Derived Endothelial-Colony Forming Cells and Their Growth Factor-Induced Sprouting Capacity. PLoS ONE, 2015;10(6):e0129935. 2015 [PMID: 26076450] (Human) Human
Ekstrom M, Liska J, Eriksson P, Sverremark-Ekstrom E, Tornvall P Stimulated in vivo synthesis of plasminogen activator inhibitor-1 in human adipose tissue. Thromb Haemost, 2012;108(3):485-92. 2012 [PMID: 22740034] (Human) Human
Dunoyer-Geindre S, Fish RJ, Kruithof EK Regulation of the endothelial plasminogen activator system by fluvastatin. Role of Rho family proteins, actin polymerisation and p38 MAP kinase. Thromb. Haemost., 2011;105(3):461-72. 2011 [PMID: 21174002] (Human) Human
Becker M, Szarvas T, Wittschier M, vom Dorp F, Totsch M, Schmid KW, Rubben H, Ergun S Prognostic impact of plasminogen activator inhibitor type 1 expression in bladder cancer. Cancer, 2010;116(19):4502-12. 2010 [PMID: 20564745] (Human) Human

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Product General Protocols

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FAQs for Serpin E1/PAI-1 (DY1786). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

Biotin DY1786

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Bioinformatics

Gene Symbol SERPINE1