Human sE-Selectin/CD62E Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Catalog# & Conjugate Size Price

Human sE-Selectin/CD62E Quantikine ELISA Kit Summary

Background
The Quantikine Human sE-Selectin immunoassay is a 4.5 hour solid phase ELISA designed to measure sE-Selectin in cell culture supernates, serum, and plasma. It contains CHO cell-expressed recombinant human sE-Selectin and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human sE-Selectin showed linear curves that were parallel to the standard curv...es obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human sE-Selectin.
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Specificity
Natural and recombinant human sE-Selectin
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
SELE

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DSLE00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human sE-Selectin/CD62E Quantikine ELISA Kit

  • CD62 antigen-like family member E
  • CD62E antigen
  • CD62E
  • ELAM
  • ELAM1
  • ELAM-1
  • ELAM1E-selectin
  • endothelial adhesion molecule 1
  • Endothelial leukocyte adhesion molecule 1
  • ESEL
  • E-Selectin
  • LECAM2
  • leukocyte endothelial cell adhesion molecule 2
  • Leukocyte-endothelial cell adhesion molecule 2
  • SELE
  • selectin E

Background

The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin. E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The human and rat proteins share approximately 67% amino acid sequence identity. The mouse and rat proteins share approximately 78% amino acid sequence identity. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes. Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. Human and mouse L-Selectin share 76% amino acid sequence identity. Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P) is expressed by activated platelets and endothelial cells. The extracellular domains of human and mouse P-Selectin share approximately 73% amino acid sequence identity.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for E-Selectin/CD62E (DSLE00)(36)

We have publications tested in 1 confirmed species: Human.


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Human
(36)
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Showing Publications 1 - 10 of 36. Show All 36 Publications.
Publications using DSLE00 Applications Species
L Garabet, CE Henriksson, ML Lozano, W Ghanima, J Bussel, E Brodin, MP Fernández-, C Martínez, R González-C, MC Mowinckel, PM Sandset Markers of endothelial cell activation and neutrophil extracellular traps are elevated in immune thrombocytopenia but are not enhanced by thrombopoietin receptor agonists Thromb. Res., 2019;185(0):119-124. 2019 [PMID: 31805421] (Human) Human
JE Guevara, KW Murdock High social strain and physical health: Examining the roles of anxious arousal, body mass index, and inflammation Psychoneuroendocrinology, 2019;106(0):155-160. 2019 [PMID: 30986751] (Human) Human
A Manichaiku, XQ Wang, L Li, J Erdmann, G Lettre, JC Bis, D Waterworth, M Cushman, NS Jenny, WS Post, W Palmas, MY Tsai, L Wallentin, H White, H Schunkert, CJ O'Donnell, DM Herrington, SS Rich, ML O'Donoghue, A Rodriguez Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease PLoS ONE, 2018;13(10):e0204352. 2018 [PMID: 30289950] (Human) Human
IA Muntean, IC Bocsan, N Miron, AD Buzoianu, D Deleanu How Could We Influence Systemic Inflammation in Allergic Rhinitis? The Role of H1 Antihistamines Oxid Med Cell Longev, 2018;2018(0):3718437. 2018 [PMID: 30008985] (Human) Human
N Sarabon, S Löfler, J Cvecka, W Hübl, S Zampieri Acute effect of different concentrations of cayenne pepper cataplasm on sensory-motor functions and serum levels of inflammation-related biomarkers in healthy subjects Eur J Transl Myol, 2018;28(1):7333. 2018 [PMID: 29686821] (Human) Human
DL McKay, M Eliasziw, CYO Chen, JB Blumberg A Pecan-Rich Diet Improves Cardiometabolic Risk Factors in Overweight and Obese Adults: A Randomized Controlled Trial Nutrients, 2018;10(3):. 2018 [PMID: 29534487] (Human) Human
N Askari, T Ghazanfari, MM Naghizadeh, A Moin, A Khamesipou, S Pourfarzam, ZM Hassan Evaluation of Association Between the Serum Levels of MMP-9 and MMP-9/TIMPs With Soluble Forms of Selectins and Itching Induced by Sulfur Mustard Iran J Pathol, 2017;12(3):257-264. 2017 [PMID: 29531551] (Human) Human
C Robinson, L Tsang, A Solomon, AJ Woodiwiss, S Gunter, M Mer, HC Hsu, M Gomes, GR Norton, AME Millen, PH Dessein Nesfatin-1 and visfatin expression is associated with reduced atherosclerotic disease risk in patients with rheumatoid arthritis Peptides, 2018;102(0):31-37. 2018 [PMID: 29475075] (Human) Human
N Moradi, R Fadaei, S Emamgholip, E Kazemian, G Panahi, S Vahedi, L Saed, S Fallah Association of circulating CTRP9 with soluble adhesion molecules and inflammatory markers in patients with type 2 diabetes mellitus and coronary artery disease PLoS ONE, 2018;13(1):e0192159. 2018 [PMID: 29381773] (Human) Human
L Jolly, K Carrasco, M Derive, J Lemarié, A Boufenzer, S Gibot Targeted endothelial gene deletion of Triggering Receptor Expressed on Myeloid cells-1 protects mice during septic shock Cardiovasc. Res., 2018;0(0):. 2018 [PMID: 29361046] (Human) Human
Show All 36 Publications.

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Product General Protocols

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FAQs for E-Selectin/CD62E (DSLE00). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DSLE00
HRP DSLE00
HRP DSLE00

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Bioinformatics

Gene Symbol SELE