Human RGM-A DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human RGM-A DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: RGMA

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human RGM-A DuoSet ELISA, 5 Plate

• RGM domain family member A
• RGM domain family, member A
• RGMA
• RGM-A
• RGMrepulsive guidance molecule A

Background

The repulsive guidance molecule (RGM) family of molecules contains three uniquely structured GPI-linked glycoproteins that participate in a variety of activities. Termed RGM-A, -B and -C, they are 40-45 kDa in size, show generally nonoverlapping fetal expression patterns, and serve as BMP-4 receptors. RGM-A and -C are plasma membrane bound, while RGM-B is generally microsomal in location. RGM-A and -B are associated with neurons, while RGM-C regulates skeletal muscle and hepatocyte function.

Publications for RGM-A (DY2459-05)(2)

Publications using DY2459-05

• Shimizu, M;Shiraishi, N;Tada, S;Sasaki, T;Beck, G;Nagano, S;Kinoshita, M;Sumi, H;Sugimoto, T;Ishida, Y;Koda, T;Ishikura, T;Sugiyama, Y;Kihara, K;Kanakura, M;Nakajima, T;Takeda, S;Takahashi, MP;Yamashita, T;Okuno, T;Mochizuki, H; RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS Science advances 2023-11-24 [PMID: 37992159] (Human, Mouse)
• A Körner, M Schlegel, T Kaussen, V Gudernatsc, G Hansmann, T Schumacher, M Giera, V Mirakaj Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule A Nat Commun, 2019-02-07;10(1):633. 2019-02-07 [PMID: 30733433] (Mouse)

Bioinformatics

• Gene Symbol: RGMA