Human IGFBP-2 DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Human IGFBP-2 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
IGFBP2

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY674.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IGFBP-2 DuoSet ELISA, 15 Plate

  • BP2
  • IBP2
  • IBP-2
  • IGF-binding protein 2
  • IGFBP2
  • IGFBP-2
  • IGF-BP53
  • insulin-like growth factor binding protein 2 (36kD)
  • insulin-like growth factor binding protein 2, 36kDa
  • insulin-like growth factor-binding protein 2

Background

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.

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Publications for IGFBP-2 (DY674)(8)

We have publications tested in 1 confirmed species: Human.


Filter By Application
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Human
(8)
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Showing Publications 1 - 8 of 8.
Publications using DY674 Applications Species
YJ Park, SJ Woo, YM Kim, S Hong, YE Lee, KH Park Immune and Inflammatory Proteins in Cord Blood as Predictive Biomarkers of Retinopathy of Prematurity in Preterm Infants Invest. Ophthalmol. Vis. Sci., 2019;60(12):3813-3820. 2019 [PMID: 31525777] (Human) Human
Y Liu, F Li, YT Yang, XD Xu, JS Chen, TL Chen, HJ Chen, YB Zhu, JY Lin, Y Li, XM Xie, XL Sun, YQ Ke IGFBP2 promotes vasculogenic mimicry formation via regulating CD144 and MMP2 expression in glioma Oncogene, 2018;0(0):. 2018 [PMID: 30368528] (Human) Human
Deregulation of IGF-binding proteins -2 and -5 contributes to the development of endocrine resistant breast cancer in vitro Oncotarget, 2016;7(22):32129-43. 2016 [PMID: 27050076] (Human) Human
CC Mok, HH Ding, M Kharboutli, C Mohan Axl, Ferritin, Insulin-Like Growth Factor Binding Protein 2, and Tumor Necrosis Factor Receptor Type II as Biomarkers in Systemic Lupus Erythematosus Arthritis Care Res (Hoboken), 2016;68(9):1303-9. 2016 [PMID: 26749069] (Human) Human
Yau S, Russo V, Clarke I, Dunshea F, Werther G, Sabin M IGFBP-2 inhibits adipogenesis and lipogenesis in human visceral, but not subcutaneous, adipocytes. Int J Obes (Lond), 2015;39(5):770-81. 2015 [PMID: 25370576] (Human) Human
Migita T, Narita T, Asaka R, Miyagi E, Nagano H, Nomura K, Matsuura M, Satoh Y, Okumura S, Nakagawa K, Seimiya H, Ishikawa Y Role of insulin-like growth factor binding protein 2 in lung adenocarcinoma: IGF-independent antiapoptotic effect via caspase-3. Am. J. Pathol., 2010;176(4):1756-66. 2010 [PMID: 20150439] (Human) Human
Pitteri SJ, JeBailey L, Faca VM, Thorpe JD, Silva MA, Ireton RC, Horton MB, Wang H, Pruitt LC, Zhang Q, Cheng KH, Urban N, Hanash SM, Dinulescu DM Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery. PLoS ONE, 2009;4(11):e7916. 2009 [PMID: 19936259] (Human) Human
Eiseman JL, Guo J, Ramanathan RK, Belani CP, Solit DB, Scher HI, Ivy SP, Zuhowski EG, Egorin MJ Evaluation of plasma insulin-like growth factor binding protein 2 and Her-2 extracellular domain as biomarkers for 17-allylamino-17-demethoxygeldanamycin treatment of adult patients with advanced solid tumors. Clin. Cancer Res., 2007;13(7):2121-7. 2007 [PMID: 17404095] (Human) Human

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FAQs for IGFBP-2 (DY674). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.
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Bioinformatics

Gene Symbol IGFBP2