Human HGFR/c-MET DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human HGFR/c-MET DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: MET

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human HGFR/c-MET DuoSet ELISA, 15 Plate

• AUTS9
• cMET
• c-MET
• EC 2.7.10
• EC 2.7.10.1
• hepatocyte growth factor receptor
• HGF R
• HGF receptor
• HGF/SF receptor
• HGFR
• Met (c-Met)
• met proto-oncogene (hepatocyte growth factor receptor)
• met proto-oncogene tyrosine kinase
• MET
• oncogene MET
• Proto-oncogene c-Met
• RCCP2
• Scatter factor receptor
• SF receptor
• Tyrosine-protein kinase Met

Background

HGF receptor, a product of the proto-oncogene c-met, is a heterodimeric transmembrane glycoprotein that is a receptor-type tyrosine kinase. c-MET is synthesized as a single-chain precursor (pr170) which undergoes post-translational glycosylation and proteolytic cleavage to give rise to the heterodimeric mature form.

Publications for HGFR/c-MET (DY358)(8)

Publications using DY358

• D Keresztes, A Csizmarik, N Nagy, O Módos, T Fazekas, T Bracht, B Sitek, K Witzke, M Puhr, S Sevcenco, G Kramer, S Shariat, Z Küronya, L Takács, I Tornyi, J Lázár, B Hadaschik, A Lászik, M Sz?cs, P Nyirády, T Szarvas Comparative proteome analysis identified CD44 as a possible serum marker for docetaxel resistance in castration-resistant prostate cancer Journal of Cellular and Molecular Medicine, 2021-12-30;0(0):. 2021-12-30 [PMID: 34970839] (Human)
• SJ Wang, R Li, TSC Ng, G Luthria, MJ Oudin, M Prytyskach, RH Kohler, R Weissleder, DA Lauffenbur, MA Miller Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy Sci Adv, 2020-05-22;6(21):eaaz8521. 2020-05-22 [PMID: 32494745] (Human)
• H Park, D Kim, E Kim, JK Sa, HW Lee, S Yu, J Oh, SH Kim, Y Yoon, DH Nam Tumor Inhibitory Effect of IRCR201, a Novel Cross-Reactive c-Met Antibody Targeting the PSI Domain Int J Mol Sci, 2017-09-13;18(9):. 2017-09-13 [PMID: 28902178] (Human)
• ADAM17 substrate release in proximal tubule drives kidney fibrosis JCI Insight, 2016-08-18;1(13):. 2016-08-18 [PMID: 27642633] (Human)
• Lee , J M, Kim , B, Lee , S B, Jeong , Y, Oh , Y M, Song , Y-J, Jung , S, Choi , J, Lee , S, Cheong , K H, Kim , D U, Park , H W, Han , Y K, Kim , G W, Choi , H, Song , P H, Kim , K A Cbl-independent degradation of Met: ways to avoid agonism of bivalent Met-targeting antibody. Oncogene, 2012-12-03;33(1):34-43. 2012-12-03 [PMID: 23208509] (Human)
• Pitteri SJ, JeBailey L, Faca VM, Thorpe JD, Silva MA, Ireton RC, Horton MB, Wang H, Pruitt LC, Zhang Q, Cheng KH, Urban N, Hanash SM, Dinulescu DM Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery. PLoS ONE, 2009-11-19;4(11):e7916. 2009-11-19 [PMID: 19936259] (Human)
• Zeng X, Sun Y, Yang HX, Li D, Li YX, Liao QP, Wang YL Plasma level of soluble c-Met is tightly associated with the clinical risk of preeclampsia. Am. J. Obstet. Gynecol., 2009-09-20;201(6):618.e1-7. 2009-09-20 [PMID: 19766985] (Human)
• Russo AL, Jedlicka K, Wernick M, McNally D, Kirk M, Sproull M, Smith S, Shankavaram U, Kaushal A, Figg WD, Dahut W, Citrin D, Bottaro DP, Albert PS, Tofilon PJ, Camphausen K Urine analysis and protein networking identify met as a marker of metastatic prostate cancer. Clin. Cancer Res., 2009-06-23;15(13):4292-8. 2009-06-23 [PMID: 19549766] (Human)

FAQs for HGFR/c-MET (DY358). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: MET