Human FGF-19 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human FGF-19 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: FGF19

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human FGF-19 DuoSet ELISA, 15 Plate

• FGF19
• FGF-19
• fibroblast growth factor 19

Background

FGF-19 (Fibroblast Growth Factor-19) is a secreted heparin-binding protein in the endocrine subfamily of FGFs that also includes FGF-21 and FGF-23. It is produced by epithelial cells of the ileal intestine in response to bile acids and signals through a receptor complex of FGF R4 and Klotho-beta in the liver. FGF-19 suppresses bile acid synthesis and enhances hepatic protein and glycogen synthesis. Dysregulalted FGF-19 activity is associated with the development of hypercholesterolemia, gall stones, bile acid induced diarrhoea (BAD), hepatocellular cancer, colon cancer, and metabolic syndrome.

Publications for FGF-19 (DY969)(2)

Publications using DY969

• Castañé, H;Jiménez-Franco, A;Hernández-Aguilera, A;Martínez-Navidad, C;Cambra-Cortés, V;Onoiu, AI;Jiménez-Aguilar, JM;París, M;Hernández, M;Parada, D;Guilarte, C;Zorzano, A;Hernández-Alvarez, MI;Camps, J;Joven, J; Multi-omics profiling reveals altered mitochondrial metabolism in adipose tissue from patients with metabolic dysfunction-associated steatohepatitis EBioMedicine 2025-01-01 [PMID: 39731853] (Human)
• CM Fallon, JS Smyth, A Quach, N Lajczak-Mc, A O'Toole, KE Barrett, H Sheridan, SJ Keely Pentacyclic triterpenes modulate farnesoid X receptor expression in colonic epithelial cells: implications for colonic secretory function The Journal of Biological Chemistry, 2022-10-06;0(0):102569. 2022-10-06 [PMID: 36209824] (Human)

FAQs for FGF-19 (DY969). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: FGF19