Human EMMPRIN/CD147 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human EMMPRIN/CD147 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: BSG

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human EMMPRIN/CD147 DuoSet ELISA, 15 Plate

• 5F7
• basigin (Ok blood group)
• Basigin
• BSG
• CD147 antigen
• CD147
• Collagenase stimulatory factor
• EMMPRIN
• EMMPRINTCSF
• Extracellular matrix metalloproteinase inducer
• Leukocyte activation antigen M6
• M6
• OK blood group antigen
• OK
• Tumor cell-derived collagenase stimulatory factor

Background

The name EMMPRIN reflects this proteins extracellular metalloproteinase inducer activity. It is a cell surface protein with two extracellular Ig domains, a transmembrane domain, and a cytoplasmic domain. Its expression is often elevated in human tumor cells, which in turn promotes MMP-1, MMP-2 and MMP-3 production in melanoma cells and MMP-2 and MMP-9 production in breast cancer cells. It interacts with several types of molecules such as integrins, caveolin-1 and MCT1. TRA-1-85 is an epitope within EMMPRIN.

Publications for EMMPRIN/CD147 (DY972)(6)

Publications using DY972

• Zisman, D;Sabtan, H;Rahat, MM;Simanovich, E;Haddad, A;Gazitt, T;Feld, J;Slobodin, G;Kibari, A;Elias, M;Rahat, MA; Tofacitinib Regulates Endostatin via Effects on CD147 and Cathepsin S International journal of molecular sciences 2024-07-02 [PMID: 39000375] (Human)
• Ghandour, F;Kassem, S;Simanovich, E;Rahat, M; Glucose Promotes EMMPRIN/CD147 and the Secretion of Pro-Angiogenic Factors in a Co-Culture System of Endothelial Cells and Monocytes Biomedicines 2024-03-22 [PMID: 38672062] (Human)
• April Rees, Steve Turner, Catherine A. Thornton Potential protective effects of breast milk and amniotic fluid against novel coronavirus SARS‐CoV‐2 through decoy receptors Pediatric Allergy and Immunology 2022-01-01 [PMID: 34585801] (Human)
• MA Rahat, M Safieh, E Simanovich, E Pasand, T Gazitt, A Haddad, M Elias, D Zisman The role of EMMPRIN/CD147 in regulating angiogenesis in patients with psoriatic arthritis Arthritis Res Ther, 2020-10-14;22(1):240. 2020-10-14 [PMID: 33054815] (Human)
• M Kusunoki, E Sata, K Nishio, T Tanaka, T Nishida, N Sugano, S Sato, M Asano Acid-electrolyzed functional water induces extracellular matrix metalloproteinase inducer, a possible novel alarmin, secretion from oral squamous cell carcinoma cell lines Int J Med Sci, 2018-09-07;15(12):1365-1372. 2018-09-07 [PMID: 30275765] (Human)
• A Saiki, M Motoyoshi, K Motozawa, T Okamura, K Ueki, N Shimizu, M Asano EMMPRIN Inhibits bFGF-Induced IL-6 Secretion in an Osteoblastic Cell Line, MC3T3-E1 Int J Med Sci, 2017-09-19;14(12):1173-1180. 2017-09-19 [PMID: 29104472] (Human)

FAQs for EMMPRIN/CD147 (DY972). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: BSG