Human CXCL6/GCP-2 Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human CXCL6/GCP-2 Quantikine ELISA Kit Summary

Background
The Quantikine Human GCP-2 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human GCP-2 in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human GCP-2 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human GCP-2 showed linear curves that were parallel to the standard curves obtaine...d using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural GCP-2.
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Specificity
Natural and recombinant human GCP-2
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
CXCL6

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DGC00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CXCL6/GCP-2 Quantikine ELISA Kit

  • chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
  • Chemokine alpha 3
  • CKA-3Granulocyte chemotactic protein 2
  • CXCL6
  • GCP-2
  • GCP2member 6 (granulocytechemotactic protein 2)
  • GCP-2Small-inducible cytokine B6
  • Small inducible cytokine subfamily B (Cys-X-Cys), member b

Background

GCP-2 (granulocyte chemotactic protein-2) is a CXC chemokine. Among human CXC chemokines, GCP-2 is most closely related to ENA-78. The structure and sequence of the genes for human GCP-2 and ENA-78 also exhibit close similarity, suggesting the two genes may have originated from a recent gene duplication. LIX (LPS-induced CXC chemokine) was initially cloned as a gene induced by LPS in mouse fibroblasts. The mouse protein designated GCP-2, because of its amino acid sequence similarity (60%) to human GCP-2, is identical to the LIX protein sequence.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CXCL6/GCP-2 (DGC00)(8)

We have publications tested in 1 confirmed species: Human.


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Human
(8)
All Species
Showing Publications 1 - 8 of 8.
Publications using DGC00 Applications Species
MJ Sebastião, M Serra, R Pereira, I Palacios, P Gomes-Alve, PM Alves Human cardiac progenitor cell activation and regeneration mechanisms: exploring a novel myocardial ischemia/reperfusion in vitro model Stem Cell Res Ther, 2019;10(1):77. 2019 [PMID: 30845956] (Human) Human
SL Fossum, MJ Mutolo, A Tugores, S Ghosh, SH Randell, LC Jones, SH Leir, A Harris Ets Homologous Factor (EHF) has Critical Roles in Epithelial Dysfunction in Airway Disease J. Biol. Chem., 2017;0(0):. 2017 [PMID: 28461336] (Human) Human
Rudisch A, Dewhurst M, Horga L, Kramer N, Harrer N, Dong M, van der Kuip H, Wernitznig A, Bernthaler A, Dolznig H, Sommergruber W High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFkappaB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts. PLoS ONE, 0;10(4):e0124283. 0 [PMID: 25919140] (Human) Human
Matsuda A, Fukuda S, Matsumoto K, Saito H Th1/Th2 cytokines reciprocally regulate in vitro pulmonary angiogenesis via CXC chemokine synthesis. Am. J. Respir. Cell Mol. Biol., 2007;38(2):168-75. 2007 [PMID: 17709600] (Human) Human
Abe Y, Fornage M, Yang CY, Bui-Thanh NA, Wise V, Chen HH, Rangaraj G, Ballantyne CM L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion. Atherosclerosis, 2007;192(1):56-66. 2007 [PMID: 17022986] (Human) Human
Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J. Immunol., 2005;175(9):6177-89. 2005 [PMID: 16237115] (Human) Human
Gessler P, Pretre R, Hohl V, Rousson V, Fischer J, Dahinden C CXC-chemokine stimulation of neutrophils correlates with plasma levels of myeloperoxidase and lactoferrin and contributes to clinical outcome after pediatric cardiac surgery. Shock, 2004;22(6):513-20. 2004 [PMID: 15545821] (Human) Human
Maheshwari A, Christensen RD, Calhoun DA ELR+ CXC chemokines in human milk. Cytokine, 2003;24(3):91-102. 2003 [PMID: 14581003] (Human) Human

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Bioinformatics

Gene Symbol CXCL6