Human CXCL6/GCP-2 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human CXCL6/GCP-2 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CXCL6

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CXCL6/GCP-2 DuoSet ELISA, 15 Plate

• chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
• Chemokine alpha 3
• CKA-3Granulocyte chemotactic protein 2
• CXCL6
• GCP-2
• GCP2member 6 (granulocytechemotactic protein 2)
• GCP-2Small-inducible cytokine B6
• Small inducible cytokine subfamily B (Cys-X-Cys), member b

Background

GCP-2 (granulocyte chemotactic protein-2) is a CXC chemokine. Among human CXC chemokines, GCP-2 is most closely related to ENA-78. The structure and sequence of the genes for human GCP-2 and ENA-78 also exhibit close similarity, suggesting the two genes may have originated from a recent gene duplication. LIX (LPS-induced CXC chemokine) was initially cloned as a gene induced by LPS in mouse fibroblasts. The mouse protein designated GCP-2, because of its amino acid sequence similarity (60%) to human GCP-2, is identical to the LIX protein sequence.

Publications for CXCL6/GCP-2 (DY333)(6)

Publications using DY333

• Mahadeo, A;Bammler, TK;MacDonald, J;Zheng, AR;Yeung, CK;Himmelfarb, J;Kelly, EJ; Evaluation of toxicological mechanisms of ochratoxin-A in human primary proximal tubule epithelial cells bioRxiv : the preprint server for biology 2025-09-04 [PMID: 40950123] (Human)
• J Wan, S Liu, W Sun, H Yu, W Tang, W Liu, J Ji, B Liu Ring finger protein 152-dependent degradation of TSPAN12 suppresses hepatocellular carcinoma progression Cancer Cell International, 2021-02-18;21(1):122. 2021-02-18 [PMID: 33602225] (Human)
• Parola C, Salogni L, Vaira X, Scutera S, Somma P, Salvi V, Musso T, Tabbia G, Bardessono M, Pasquali C, Mantovani A, Sozzani S, Bosisio D Selective activation of human dendritic cells by OM-85 through a NF-kB and MAPK dependent pathway. PLoS ONE, 2013-12-30;8(12):e82867. 2013-12-30 [PMID: 24386121] (Human)
• Hawn TR, Scholes D, Wang H, Li SS, Stapleton AE, Janer M, Aderem A, Stamm WE, Zhao LP, Hooton TM Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women. PLoS ONE, 2009-12-15;4(12):e8300. 2009-12-15 [PMID: 20016852] (Human)
• Begley LA, Kasina S, Macdonald J, Macoska JA The inflammatory microenvironment of the aging prostate facilitates cellular proliferation and hypertrophy. Cytokine, 2008-06-24;43(2):194-9. 2008-06-24 [PMID: 18572414] (Human)
• Pierer M, Rethage J, Seibl R, Lauener R, Brentano F, Wagner U, Hantzschel H, Michel BA, Gay RE, Gay S, Kyburz D Chemokine secretion of rheumatoid arthritis synovial fibroblasts stimulated by Toll-like receptor 2 ligands. J. Immunol., 2004-01-15;172(2):1256-65. 2004-01-15 [PMID: 14707104] (Human)

FAQs for CXCL6/GCP-2 (DY333). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: CXCL6