Human CXCL2/GRO beta DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human CXCL2/GRO beta DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CXCL2/GRO beta DuoSet ELISA, 5 Plate

• chemokine (C-X-C motif) ligand 2
• CINC-2a
• CINC3
• CINC-3
• C-X-C Motif Chemokine 2
• CXCL2
• GRO beta
• GRO2 oncogene
• GRO2
• GROB
• Gro-beta
• Growth-regulated protein beta
• Macrophage inflammatory protein 2-alpha
• melanoma growth stimulatory activity beta
• MGSA beta
• MGSA-b
• MGSA-beta
• MIP2
• MIP-2
• MIP2A
• MIP-2a
• MIP2-alpha
• SCYB2

Background

CXCL2/GRO beta, also called MIP-2 in mouse and CINC-3 in rat, is a member of the CXC chemokine family. Human CXCL2/GRO beta is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 70% and 71% aa sequence identity with the human protein, respectively. N-terminal aa 1-4 of CXCL2/GRO beta can be post-translationally cleaved which confers enhanced hematopoietic bioactivity. CXCL2/GRO beta is produced by a variety of cell types including monocytes and macrophages at sites of inflammation and is chemotactic for granulocytes, including neutrophils.

Publications for CXCL2/GRO beta/MIP-2/CINC-3 (DY276-05)(14)

Publications using DY276-05

• Shepelkova, GS;Evstifeev, VV;Berezovskiy, YS;Ergeshova, AE;Tarasov, RV;Bagirov, MA;Yeremeev, VV; Characteristics of Pulmonary Inflammation in Patients with Different Forms of Active Tuberculosis International journal of molecular sciences 2024-11-02 [PMID: 39519346] (Human)
• Virard, F;Giraud, S;Bonnet, M;Magadoux, L;Martin, L;Pham, TH;Skafi, N;Deneuve, S;Frem, R;Villoutreix, BO;Sleiman, NH;Reboulet, J;Merabet, S;Chaptal, V;Chaveroux, C;Hussein, N;Aznar, N;Fenouil, T;Treilleux, I;Saintigny, P;Ansieau, S;Manié, S;Lebecque, S;Renno, T;Coste, I; Targeting ERK-MYD88 interaction leads to ERK dysregulation and immunogenic cancer cell death Nature communications 2024-08-15 [PMID: 39147750] (Human)
• Zobel, CM;Wenzel, W;Krüger, JP;Baumgarten, U;Wagelöhner, T;Neumann, N;Foroutan, B;Müller, R;Müller, A;Rauschning, D;Schü beta ler, M;Scheit, L;Weinreich, F;Oltmanns, K;Keidel, F;Koch, M;Spethmann, S;Schreiner, M; Serum interleukin-6, procalcitonin, and C-reactive protein at hospital admission can identify patients at low risk for severe COVID-19 progression Frontiers in microbiology 2023-10-23 [PMID: 37937220] (Human)
• Liu, Y;Smith, MR;Wang, Y;D'Agostino, R;Ruiz, J;Lycan, T;Kucera, GL;Miller, LD;Li, W;Chan, MD;Farris, M;Su, J;Song, Q;Zhao, D;Chandrasekaran, A;Xing, F; c-Met Mediated Cytokine Network Promotes Brain Metastasis of Breast Cancer by Remodeling Neutrophil Activities Cancers 2023-05-05 [PMID: 37174093]
• J Yang, L Jin, HS Kim, F Tian, Z Yi, K Bedi, M Ljungman, M Pasca di M, H Crawford, J Shi KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer Cancer Research, 2022-11-15;0(0):OF1-OF14. 2022-11-15 [PMID: 36306422] (Human)
• MS Shaban, C Müller, C Mayr-Buro, H Weiser, J Meier-Soel, BV Albert, A Weber, U Linne, T Hain, I Babayev, N Karl, N Hofmann, S Becker, S Herold, ML Schmitz, J Ziebuhr, M Kracht Multi-level inhibition of coronavirus replication by chemical ER stress Nature Communications, 2021-09-20;12(1):5536. 2021-09-20 [PMID: 34545074] (Human)
• HK Skovdahl, S Gopalakris, TD Svendsen, AVB Granlund, I Bakke, ZG Ginbot, S Thorsvik, A Flatberg, B Sporsheim, J Ostrop, TE Mollnes, AK Sandvik, T Bruland Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration Frontiers in Pharmacology, 2021-05-13;12(0):679741. 2021-05-13 [PMID: 34054553] (Human)
• ID Green, N Pinello, R Song, Q Lee, JM Halstead, CT Kwok, ACH Wong, SS Nair, SJ Clark, B Roediger, U Schmitz, M Larance, R Hayashi, JEJ Rasko, JJ Wong Macrophage development and activation involve coordinated intron retention in key inflammatory regulators Nucleic Acids Res., 2020-07-09;0(0):. 2020-07-09 [PMID: 32449925] (Human)
• L Kloss, C Dollt, K Schledzews, A Krewer, S Melchers, C Manta, C Sticht, C Torre, J Utikal, V Umansky, A Schmieder ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12 Cell Death Dis, 2019-10-07;10(10):760. 2019-10-07 [PMID: 31591378] (Human)
• S Giuliano, M Dufies, PD Ndiaye, J Viotti, D Borchielli, J Parola, V Vial, Y Cormerais, M Ohanna, V Imbert, E Chamorey, N Rioux-Lecl, A Savina, JM Ferrero, B Mograbi, G Pagès Resistance to lysosomotropic drugs used to treat kidney and breast cancers involves autophagy and inflammation and converges in inducing CXCL5 Theranostics, 2019-01-30;9(4):1181-1199. 2019-01-30 [PMID: 30867824] (Human)
• SA Ingelse, J Juschten, MAW Maas, G Matute-Bel, NP Juffermans, JBM van Woense, RA Bem Fluid restriction reduces pulmonary edema in a model of acute lung injury in mechanically ventilated rats PLoS ONE, 2019-01-17;14(1):e0210172. 2019-01-17 [PMID: 30653512] (Human)
• A Zukauskas, RJ Mrsny, P Cortés Bar, JR Turner, JM Leong, BA McCormick Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection mSphere, 2018-07-05;3(4):. 2018-07-05 [PMID: 29976647] (Human)
• F Olaru, T Döbel, AS Lonsdorf, S Oehrl, M Maas, AH Enk, M Schmitz, EF Gröne, HJ Gröne, K Schäkel Intracapillary immune complexes recruit and activate slan-expressing CD16+ monocytes in human lupus nephritis JCI Insight, 2018-06-07;3(11):. 2018-06-07 [PMID: 29875315] (Human)
• Xian K Zhang The Fli-1 transcription factor is a critical regulator for controlling the expression of chemokine C-X-C motif ligand 2 (CXCL2) Mol. Immunol., 2016-11-24;81(0):59-66. 2016-11-24 [PMID: 27889620] (Human)

FAQs for CXCL2/GRO beta/MIP-2/CINC-3 (DY276-05). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.