Human CCL24/Eotaxin-2/MPIF-2 Quantikine ELISA Kit

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP

Human CCL24/Eotaxin-2/MPIF-2 Quantikine ELISA Kit Summary

• Background: The Quantikine Human Eotaxin-2 Immunoassay is a 4.5 hour solid phase ELISA designed to measure Eotaxin-2 levels in cell culture supernates, serum, and plasma. It contains E.coli-expressed recombinant human Eotaxin-2 and antibodies raised against the recombinant factor. Results obtained for naturally occurring human Eotaxin-2 showed linear curves that were parallel to the standard cu...rves obtained using the kit standards. These results indicate that this kit can be used to determine relative mass values for natural human Eotaxin-2.
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• Specificity: Natural and recombinant human Eotaxin-2
• Source: N/A
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CCL24

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CCL24/Eotaxin-2/MPIF-2 Quantikine ELISA Kit

• CCL24
• chemokine (C-C motif) ligand 24
• Ckb-6
• Eosinophil chemotactic protein 2
• Eotaxin-2
• member 24
• MPIF2
• MPIF-2
• MPIF2Myeloid progenitor inhibitory factor 2
• MPIF-2Small-inducible cytokine A24
• SCYA24CK-beta-6

Background

Eotaxin-2, also named myeloid progenitor inhibitory factor 2 (MPIF-2), is a member of the CC chemokine subfamily and is designated CCL24. Eotaxin-2 is constitutively expressed in the jejunum and spleen. It can also be induced in the lung by allergen challenge and IL-4. Mouse Eotaxin-2 precursor protein shares approximately 58% amino acid sequence identity with human Eotaxin-2.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CCL24/Eotaxin-2/MPIF-2 (DCC240B)(15)

Publications using DCC240B

• Tsai, HF;Tseng, CF;Liang, YL;Wu, PY;Huang, LY;Lin, YH;Lin, LH;Lin, CN;Hsu, KF; Downregulation of Salt-Inducible Kinase 3 Enhances CCL24 Activation in the Placental Environment with Preeclampsia International journal of molecular sciences 2023-12-22 [PMID: 38203391] (Human)
• SJ Ackerman, AF Kagalwalla, I Hirano, N Gonsalves, PM Katcher, S Gupta, JB Wechsler, M Grozdanovi, Z Pan, JC Masterson, J Du, RJ Fantus, P Alumkal, JJ Lee, S Ochkur, F Ahmed, K Capocelli, H Melin-Alda, K Biette, A Dubner, K Amsden, K Keeley, M Sulkowski, A Zalewski, D Atkins, GT Furuta One-Hour Esophageal String Test: A Nonendoscopic Minimally Invasive Test That Accurately Detects Disease Activity in Eosinophilic Esophagitis Am. J. Gastroenterol., 2019-10-01;114(10):1614-1625. 2019-10-01 [PMID: 31567192] (Human)
• MW Han, SH Kim, I Oh, YH Kim, J Lee Serum IL-1 β can be a biomarker in children with severe persistent allergic rhinitis Allergy Asthma Clin Immunol, 2019-09-18;15(0):58. 2019-09-18 [PMID: 31548841] (Human)
• Pallis F, Conran N, Fertrin K, Olalla Saad S, Costa F, Franco-Penteado C Hydroxycarbamide reduces eosinophil adhesion and degranulation in sickle cell anaemia patients. Br J Haematol, 2013-10-28;164(2):286-95. 2013-10-28 [PMID: 24383847] (Human)
• Provost V, Langlois A, Chouinard F, Rola-Pleszczynski M, Chakir J, Flamand N, Laviolette M Leukotriene D4 and interleukin-13 cooperate to increase the release of eotaxin-3 by airway epithelial cells. PLoS ONE, 2012-08-31;7(8):e43544. 2012-08-31 [PMID: 22952702] (Human)
• Kagami S, Kai H, Kakinuma T High Levels of CCL26 in Blister Fluid and Sera of Patients with Bullous Pemphigoid. J. Invest. Dermatol., 2011-09-01;132(1):249-51. 2011-09-01 [PMID: 21881593] (Human)
• Taka E, Errahali YJ, Abonyo BO, Bauer DM, Heiman AS Post-transcriptional silencing of CCR3 downregulates IL-4 stimulated release of eotaxin-3 (CCL26) and other CCR3 ligands in alveolar type II cells. Cytokine, 2008-11-26;44(3):342-51. 2008-11-26 [PMID: 19038554] (Human)
• Makowska JS, Grzegorczyk J, Bienkiewicz B, Wozniak M, Kowalski ML Systemic responses after bronchial aspirin challenge in sensitive patients with asthma. J. Allergy Clin. Immunol., 2007-12-20;121(2):348-54. 2007-12-20 [PMID: 18086495] (Human)
• Miller M, Ramsdell J, Friedman PJ, Cho JY, Renvall M, Broide DH Computed tomographic scan-diagnosed chronic obstructive pulmonary disease-emphysema: eotaxin-1 is associated with bronchodilator response and extent of emphysema. J. Allergy Clin. Immunol., 2007-11-01;120(5):1118-25. 2007-11-01 [PMID: 17983873] (Human)
• Intapan PM, Niwattayakul K, Sawanyawisuth K, Chotmongkol V, Maleewong W Cerebrospinal fluid eotaxin and eotaxin-2 levels in human eosinophilic meningitis associated with angiostrongyliasis. Cytokine, 2007-08-20;39(2):138-41. 2007-08-20 [PMID: 17703945] (Human)
• Ochkur SI, Jacobsen EA, Protheroe CA, Biechele TL, Pero RS, McGarry MP, Wang H, O'Neill KR, O'Neill KR, Colbert DC, Colby TV, Shen H, Blackburn MR, Irvin CC, Lee JJ, Lee NA Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma. J. Immunol., 2007-06-15;178(12):7879-89. 2007-06-15 [PMID: 17548626] (Human)
• Abonyo BO, Lebby KD, Tonry JH, Ahmad M, Heiman AS Modulation of eotaxin-3 (CCL26) in alveolar type II epithelial cells. Cytokine, 2007-03-09;36(5):237-44. 2007-03-09 [PMID: 17350279] (Human)
• Ancuta P, Autissier P, Wurcel A, Zaman T, Stone D, Gabuzda D CD16+ monocyte-derived macrophages activate resting T cells for HIV infection by producing CCR3 and CCR4 ligands. J. Immunol., 2006-05-15;176(10):5760-71. 2006-05-15 [PMID: 16670281] (Human)
• Falcone C, Minoretti P, D'Angelo A, Buzzi MP, Coen E, Emanuele E, Aldeghi A, Olivieri V, Geroldi D Markers of eosinophilic inflammation and risk prediction in patients with coronary artery disease. Eur. J. Clin. Invest., 2006-04-01;36(4):211-7. 2006-04-01 [PMID: 16620281] (Human)
• Kalomenidis I, Stathopoulos GT, Barnette R, Guo Y, Peebles RS, Blackwell TS, Light RW Eotaxin-3 and interleukin-5 pleural fluid levels are associated with pleural fluid eosinophilia in post-coronary artery bypass grafting pleural effusions. Chest, 2005-06-01;127(6):2094-100. 2005-06-01 [PMID: 15947325] (Human)

Bioinformatics

• Gene Symbol: CCL24