Human CCL2/MCP-1 DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Human CCL2/MCP-1 DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
CCL2

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY279.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CCL2/MCP-1 DuoSet ELISA, 15 Plate

  • C-C motif chemokine ligand 2
  • CCL2
  • GDCF-2
  • HC11
  • HSMCR30
  • MCAF
  • Mcp1
  • MCP-1
  • SCYA2
  • SMC-CF

Background

CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.

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Publications for CCL2/JE/MCP-1 (DY279)(155)

We have publications tested in 4 confirmed species: Human, Bovine, Transgenic Mouse,  Human.


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Filter By Species
Human
(152)
Bovine
(1)
Transgenic Mouse
(1)
 Human
(1)
All Species
Showing Publications 1 - 10 of 155. Show All 155 Publications.
Publications using DY279 Applications Species
Gkiokas, A;Papadatou-Gigante, M;Gkioka, AI;Koudouna, A;Tryfou, TM;Alexandropoulos, A;Bartzi, V;Kafasi, N;Kyrtsonis, MC; Tumor-Associated Macrophage (TAM)-Related Cytokines, sCD163, CCL2, and CCL4, as Novel Biomarkers for Overall Survival and Time to Treatment in Waldenstrom's Macroglobulinemia: Emphasis on Asymptomatic WM Cells 2025-02-13 [PMID: 39996747] (Human) Human
Rezaei, A;Pourfarzam, S;Jamali, T;Mohammadi, NG;Andalib, A;Hassan, ZM;Ayubi, F;Ghazanfari, T; Exploring chemokines and soluble adhesion molecules in mustard lung pathogenesis International immunopharmacology 2025-02-08 [PMID: 39923581] (Human) Human
Navas, A;Matzaraki, V;van Eekeren, LE;Blaauw, MJT;Groenendijk, AL;Vos, WAJW;Jacobs-Cleophas, M;Dos Santos, JC;van der Ven, AJAM;Joosten, LAB;Netea, MG; Plasma Proteomic Signature as a Predictor of Age Advancement in People Living With HIV Aging cell 2025-01-15 [PMID: 39812213] (Human) Human
Chen, HK;Chen, YL;Chung, WP;Loh, ZJ;Lee, KT;Hsu, HP; Circulating CD3+CD8+ T Lymphocytes as Indicators of Disease Status in Patients With Early Breast Cancer Cancer medicine 2025-01-01 [PMID: 39749673] (Human) Human
Bekirian, C;Valsecchi, I;Bachellier-Bassi, S;Scandola, C;Guijarro, JI;Chauvel, M;Mourer, T;Gow, NAR;Aimanianda, VK;d'Enfert, C;Fontaine, T; ?-1,6-Glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall eLife 2024-12-05 [PMID: 39636210] (Human) Human
Iaia, N;Canzoneri, F;Biasi, F;Poli, G;Menta, R;Testa, G;Gamba, P; The CaCo-2 cell junction derangement exerted by the single addition of oxysterols commonly detected in foods is markedly quenched when they are in mixture The Journal of steroid biochemistry and molecular biology 2024-11-27 [PMID: 39613194] (Human) Human
Vargas-Castro, R;García-Quiroz, J;Olmos-Ortiz, A;Avila, E;Larrea, F;Díaz, L; Calcitriol prevents SARS-CoV spike-induced inflammation in human trophoblasts through downregulating ACE2 and TMPRSS2 expression The Journal of steroid biochemistry and molecular biology 2025-01-01 [PMID: 39515592] (Human) Human
Sakwe, NI;Vuong, NB;Black, PJ;Ball, DD;Thomas, P;Beasley, HK;Hinton, A;Ochieng, J;Sakwe, AM; Annexin A6 modulates the secretion of pro-inflammatory cytokines and exosomes via interaction with SNAP23 in triple negative breast cancer cells bioRxiv : the preprint server for biology 2024-10-25 [PMID: 39484394] (Human) Human
Bagheri, V;Khorramdelazad, H;Kafi, M;Abbasifard, M; Chemokine CCL2 and its receptor CCR2 in different age groups of patients with COVID-19 BMC immunology 2024-10-26 [PMID: 39455952] (Human) Human
Hampton, TH;Barnaby, R;Roche, C;Nymon, A;Fukutani, KF;MacKenzie, TA;Stanton, BA; Gene expression responses of CF airway epithelial cells exposed to elexacaftor/tezacaftor/ivacaftor (ETI) suggest benefits beyond improved CFTR channel function bioRxiv : the preprint server for biology 2024-08-29 [PMID: 39257747] (Human) Human
Show All 155 Publications.

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Product General Protocols

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FAQs for CCL2/JE/MCP-1 (DY279). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

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Bioinformatics

Gene Symbol CCL2