Human CCL2/MCP-1 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human CCL2/MCP-1 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CCL2

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CCL2/MCP-1 DuoSet ELISA, 15 Plate

• C-C motif chemokine ligand 2
• CCL2
• GDCF-2
• HC11
• HSMCR30
• MCAF
• Mcp1
• MCP-1
• SCYA2
• SMC-CF

Background

CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.

Publications for CCL2/JE/MCP-1 (DY279)(152)

Publications using DY279

• Chen, HK;Chen, YL;Chung, WP;Loh, ZJ;Lee, KT;Hsu, HP; Circulating CD3+CD8+ T Lymphocytes as Indicators of Disease Status in Patients With Early Breast Cancer Cancer medicine 2025-01-01 [PMID: 39749673] (Human)
• Bekirian, C;Valsecchi, I;Bachellier-Bassi, S;Scandola, C;Guijarro, JI;Chauvel, M;Mourer, T;Gow, NAR;Aimanianda, VK;d'Enfert, C;Fontaine, T; ?-1,6-Glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall eLife 2024-12-05 [PMID: 39636210] (Human)
• Iaia, N;Canzoneri, F;Biasi, F;Poli, G;Menta, R;Testa, G;Gamba, P; The CaCo-2 cell junction derangement exerted by the single addition of oxysterols commonly detected in foods is markedly quenched when they are in mixture The Journal of steroid biochemistry and molecular biology 2024-11-27 [PMID: 39613194] (Human)
• Vargas-Castro, R;García-Quiroz, J;Olmos-Ortiz, A;Avila, E;Larrea, F;Díaz, L; Calcitriol prevents SARS-CoV spike-induced inflammation in human trophoblasts through downregulating ACE2 and TMPRSS2 expression The Journal of steroid biochemistry and molecular biology 2025-01-01 [PMID: 39515592] (Human)
• Sakwe, NI;Vuong, NB;Black, PJ;Ball, DD;Thomas, P;Beasley, HK;Hinton, A;Ochieng, J;Sakwe, AM; Annexin A6 modulates the secretion of pro-inflammatory cytokines and exosomes via interaction with SNAP23 in triple negative breast cancer cells bioRxiv : the preprint server for biology 2024-10-25 [PMID: 39484394] (Human)
• Bagheri, V;Khorramdelazad, H;Kafi, M;Abbasifard, M; Chemokine CCL2 and its receptor CCR2 in different age groups of patients with COVID-19 BMC immunology 2024-10-26 [PMID: 39455952] (Human)
• Hampton, TH;Barnaby, R;Roche, C;Nymon, A;Fukutani, KF;MacKenzie, TA;Stanton, BA; Gene expression responses of CF airway epithelial cells exposed to elexacaftor/tezacaftor/ivacaftor (ETI) suggest benefits beyond improved CFTR channel function bioRxiv : the preprint server for biology 2024-08-29 [PMID: 39257747] (Human)
• Pongtiwattanakul, S;Leethanakul, C;Rattanaporn, O;Thammanichanon, P;Tannukit, S; Effect of compressive force combined with vibration on CCL2 and CCL5 in human periodontal ligament cells Journal of oral biology and craniofacial research 2024-08-21 [PMID: 39252795] (Human)
• Dovrolis, N;Valatas, V;Drygiannakis, I;Filidou, E;Spathakis, M;Kandilogiannakis, L;Tarapatzi, G;Arvanitidis, K;Bamias, G;Vradelis, S;Manolopoulos, VG;Paspaliaris, V;Kolios, G; Landscape of Interactions between Stromal and Myeloid Cells in Ileal Crohn's Disease; Indications of an Important Role for Fibroblast-Derived CCL-2 Biomedicines 2024-07-26 [PMID: 39200138] (Human)
• Seo, DY;Park, JW;Kim, SH;Oh, SR;Han, SB;Kwon, OK;Ahn, KS; Effect of Isoscopoletin on Cytokine Expression in HaCaT Keratinocytes and RBL-2H3 Basophils: Preliminary Study International journal of molecular sciences 2024-06-24 [PMID: 39000019] (Human)
• Louault, K;Blavier, L;Lee, MH;Kennedy, RJ;Fernandez, GE;Pawel, BR;Asgharzadeh, S;DeClerck, YA; Nuclear factor-?B activation by transforming growth factor-?1 drives tumour microenvironment-mediated drug resistance in neuroblastoma British journal of cancer 2024-05-28 [PMID: 38806726] (Human)
• Chen, PK;Chen, YM;Chen, HH;Liao, TL;Chang, SH;Yeo, KJ;Huang, PH;Chen, DY; Association of the Reduced Levels of Monocyte Chemoattractant Protein-1 with Herpes Zoster in Rheumatoid Arthritis Patients Treated with Janus Kinase Inhibitors in a Single-Center Cohort Microorganisms 2024-05-12 [PMID: 38792802] (Human)
• Reina, J;Vallmajo-Martin, Q;Ning, J;Michi, AN;Yeung, K;Wahl, GM;Hunter, T; LHPP expression in triple-negative breast cancer promotes tumor growth and metastasis by modulating the tumor microenvironment bioRxiv : the preprint server for biology 2024-04-23 [PMID: 38712081] (Human)
• Rodríguez-Hernández, MÁ;Baena-Bustos, M;Carneros, D;Zurita-Palomo, C;Muñoz-Pinillos, P;Millán, J;Padillo, FJ;Smerdou, C;von Kobbe, C;Rose-John, S;Bustos, M; Targeting IL-6 trans-signalling by sgp130Fc attenuates severity in SARS-CoV-2 -infected mice and reduces endotheliopathy EBioMedicine 2024-04-26 [PMID: 38677182] (Transgenic Mouse)
• deKay, JT;Chepurko, E;Chepurko, V;Knudsen, L;Lord, C;Searight, M;Tsibulnikov, S;Robich, MP;Sawyer, DB;Gagnon, DJ;May, T;Riker, R;Seder, DB;Ryzhov, S; Delayed CCL23 response is associated with poor outcomes after cardiac arrest Cytokine 2024-02-06 [PMID: 38325139] (Human)
• Macrì, F;Vigorito, I;Castiglione, S;Faggiano, S;Casaburo, M;Fanotti, N;Piacentini, L;Vigetti, D;Vinci, MC;Raucci, A; High Phosphate-Induced JAK-STAT Signalling Sustains Vascular Smooth Muscle Cell Inflammation and Limits Calcification Biomolecules 2023-12-24 [PMID: 38254629] (Human)
• Sivaraman, K;Pino, P;Raussin, G;Anchisi, S;Metayer, C;Dagany, N;Held, J;Wrenger, S;Welte, T;Wurm, MJ;Wurm, FM;Olejnicka, B;Janciauskiene, S; Human PBMCs Form Lipid Droplets in Response to Spike Proteins Microorganisms 2023-11-01 [PMID: 38004695] (Human)
• Abu El-Asrar, AM;Nawaz, MI;Ahmad, A;Dillemans, L;Siddiquei, M;Allegaert, E;Gikandi, PW;De Hertogh, G;Opdenakker, G;Struyf, S; CD40 Ligand-CD40 Interaction Is an Intermediary between Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy International journal of molecular sciences 2023-10-25 [PMID: 37958563] (Human)
• Nikiforov, NG;Kirichenko, TV;Kubekina, MV;Chegodaev, YS;Zhuravlev, AD;Ilchuk, LA;Nikolaeva, MA;Arefieva, AS;Popov, MA;Verkhova, SS;Bagheri Ekta, M;Orekhov, AN; Macrophages derived from LPS-stimulated monocytes from individuals with subclinical atherosclerosis were characterized by increased pro-inflammatory activity Cytokine 2023-12-01 [PMID: 37918051] (Human)
• Montezano, AC;Camargo, LL;Mary, S;Neves, KB;Rios, FJ;Stein, R;Lopes, RA;Beattie, W;Thomson, J;Herder, V;Szemiel, AM;McFarlane, S;Palmarini, M;Touyz, RM; SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication Scientific reports 2023-08-28 [PMID: 37640791] (Human)
• Letícia Martins SANTOS, Patricia e Silva CARDOSO, Elisa Abreu DINIZ, Juliana Garuba RAHHAL, Carla Renata SIPERT Different concentrations of fetal bovine serum affect cytokine modulation in Lipopolysaccharide-activated apical papilla cells in vitro* Journal of Applied Oral Science 2023-07-24 [PMID: 37493700] (Human)
• Koncina, E;Nurmik, M;Pozdeev, VI;Gilson, C;Tsenkova, M;Begaj, R;Stang, S;Gaigneaux, A;Weindorfer, C;Rodriguez, F;Schmoetten, M;Klein, E;Karta, J;Atanasova, VS;Grzyb, K;Ullmann, P;Halder, R;Hengstschläger, M;Graas, J;Augendre, V;Karapetyan, YE;Kerger, L;Zuegel, N;Skupin, A;Haan, S;Meiser, J;Dolznig, H;Letellier, E; IL1R1+ cancer-associated fibroblasts drive tumor development and immunosuppression in colorectal cancer Nature communications 2023-07-17 [PMID: 37460545] ( Human)
• Fiorillo, A;Gallego, JJ;Casanova-Ferrer, F;Giménez-Garzó, C;Urios, A;Ballester, MP;Durbán, L;Rios, MP;Megías, J;San Miguel, T;Kosenko, E;Escudero-García, D;Benlloch, S;Felipo, V;Montoliu, C; Mild Cognitive Impairment Is Associated with Enhanced Activation of Th17 Lymphocytes in Non-Alcoholic Fatty Liver Disease International journal of molecular sciences 2023-06-20 [PMID: 37373554] (Human)
• Mohammadi, NG;Namaki, S;Hashemi, SM;Salehi, M;Ghaffarpour, S;Ghazanfari, T; Impact of the MCP-1-2518A>G polymorphism on COVID-19 severity in the Iranian population: A case-control study International immunopharmacology 2023-06-01 [PMID: 37148770] (Human)
• A Di Nardo, YL Chang, S Alimohamma, K Masuda-Kur, Z Wang, K Sriram, PA Insel Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts Cell Reports, 2023-04-28;42(5):112453. 2023-04-28 [PMID: 37120813] (Human)
• M Liu, AN Panagopoul, UM Oguz, S Samant, CH Vasa, DK Agrawal, YS Chatzizisi Role of triggering receptor expressed on myeloid cells-1 in the mechanotransduction signaling pathways that link low shear stress with inflammation Scientific Reports, 2023-03-21;13(1):4656. 2023-03-21 [PMID: 36944850] (Human)
• R Nicu, DE Ciolacu, AR Petrovici, D Rusu, M Avadanei, AC Mihaila, E Butoi, F Ciolacu 3D Matrices for Enhanced Encapsulation and Controlled Release of Anti-Inflammatory Bioactive Compounds in Wound Healing International Journal of Molecular Sciences, 2023-02-20;24(4):. 2023-02-20 [PMID: 36835619] (Human)
• KB Neves, R Alves-Lope, AC Montezano, RM Touyz Role of PARP and TRPM2 in VEGF Inhibitor-Induced Vascular Dysfunction Journal of the American Heart Association, 2023-02-20;0(0):e027769. 2023-02-20 [PMID: 36802924] (Human)
• O Korchynsky, K Yoshida, N Korchynska, J Czarnik-Kw, PP Tak, GJM Pruijn, T Isozaki, JH Ruth, PL Campbell, MA Amin, AE Koch Mammalian Glycosylation Patterns Protect Citrullinated Chemokine MCP-1/CCL2 from Partial Degradation International Journal of Molecular Sciences, 2023-01-18;24(3):. 2023-01-18 [PMID: 36768186] (Human)
• M Liu, S Samant, CH Vasa, RM Pedrigi, UM Oguz, S Ryu, T Wei, DR Anderson, DK Agrawal, YS Chatzizisi Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis PLoS ONE, 2023-01-20;18(1):e0280385. 2023-01-20 [PMID: 36662769] (Human)
• K Shabir, S Gharanei, S Orton, V Patel, P Chauhan, E Karteris, HS Randeva, JE Brown, I Kyrou Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway International Journal of Molecular Sciences, 2022-12-23;24(1):. 2022-12-23 [PMID: 36613673] (Human)
• FP Veras, GA Publio, BM Melo, DS Prado, T Norbiato, NT Cecilio, C Hiroki, LEA Damasceno, R Jung, JE Toller-Kaw, TV Martins, SF Assunção, D Lima, MG Alves, GV Vieira, LA Tavares, ALR Alves-Reze, SH Karbach, HI Nakaya, TM Cunha, CS Souza, FQ Cunha, KU Sales, A Waisman, JC Alves-Filh Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation Cell Reports, 2022-12-27;41(13):111897. 2022-12-27 [PMID: 36577385] (Human)
• VC Capetini, BJ Quintanilh, DC de Oliveir, AH Nishioka, LA de Matos, LRP Ferreira, FM Ferreira, GR Sampaio, NMA Hassimotto, FM Lajolo, RA Fock, MM Rogero Blood orange juice intake modulates plasma and PBMC microRNA expression in overweight and insulin resistance women: impact on MAPK and NFkappaB signaling pathways The Journal of nutritional biochemistry, 2022-11-26;0(0):109240. 2022-11-26 [PMID: 36442716] (Human)
• CS Rigazio, N Mariz-Pont, EP Caballero, FN Penas, NB Goren, MH Santamaría, RS Corral Involvement of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor in proinflammatory mechanisms promoting cardiovascular injury mechanisms promoting cardiovascular inflammation tThe combined action of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor increases proinflammatory mediator production by cardiomyocytes and vascular endothelial cells Microbial pathogenesis, 2022-11-12;0(0):105881. 2022-11-12 [PMID: 36379373] (Human)
• FE Rossi, AJ Maldonado, JM Cholewa, SLG Ribeiro, CA de Araújo, C Figueiredo, T Reichel, K Krüger, FS Lira, LG Minuzzi Exercise training-induced changes in immunometabolic markers in youth badminton athletes Scientific Reports, 2022-09-15;12(1):15539. 2022-09-15 [PMID: 36109571] (Human)
• E The, DM de Graaf, Y Zhai, Q Yao, L Ao, DA Fullerton, CA Dinarello, X Meng Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3 Proceedings of the National Academy of Sciences of the United States of America, 2022-08-29;119(36):e2202577119. 2022-08-29 [PMID: 36037361] (Human)
• W Cheng, G Fuernau, S Desch, A Freund, HJ Feistritze, J Pöss, P Buettner, H Thiele Circulating Monocyte Chemoattractant Protein-1 in Patients with Cardiogenic Shock Complicating Acute Myocardial Infarction Treated with Mild Hypothermia: A Biomarker Substudy of SHOCK-COOL Trial Journal of cardiovascular development and disease, 2022-08-20;9(8):. 2022-08-20 [PMID: 36005444] (Human)
• S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis Journal of ovarian research, 2022-07-26;15(1):87. 2022-07-26 [PMID: 35883110] (Human)
• A Schaffert, I Karkossa, E Ueberham, R Schlichtin, K Walter, J Arnold, M Blüher, JT Heiker, J Lehmann, M Wabitsch, BI Escher, M von Bergen, K Schubert Di-(2-ethylhexyl) phthalate substitutes accelerate human adipogenesis through PPARgamma activation and cause oxidative stress and impaired metabolic homeostasis in mature adipocytes Environment international, 2022-05-06;164(0):107279. 2022-05-06 [PMID: 35567983] (Human)
• E Filidou, L Kandilogia, G Tarapatzi, M Spathakis, P Steiropoul, D Mikroulis, K Arvanitidi, V Paspaliari, G Kolios Anti-Inflammatory and Anti-Fibrotic Effect of Immortalized Mesenchymal-Stem-Cell-Derived Conditioned Medium on Human Lung Myofibroblasts and Epithelial Cells International Journal of Molecular Sciences, 2022-04-20;23(9):. 2022-04-20 [PMID: 35562961] (Human)
• MJ Yu, C Li, SS Deng, XM Meng, RS Yao Discovery of a novel GRPR antagonist for protection against cisplatin-induced acute kidney injury Bioorganic chemistry, 2022-04-06;124(0):105794. 2022-04-06 [PMID: 35533545] (Human)
• A Divoux, E Erdos, K Whytock, TF Osborne, SR Smith Transcriptional and DNA Methylation Signatures of Subcutaneous Adipose Tissue and Adipose-Derived Stem Cells in PCOS Women Cells, 2022-03-01;11(5):. 2022-03-01 [PMID: 35269469] (Human)
• B Grüner, L Peters, A Hillenbran, P Vo beta berg, J Schweiker, EG Rollmann, LH Rodriguez, J Blumhardt, S Burkert, P Kern, C Köhler, PT Soboslay Echinococcus multilocularis specific antibody, systemic cytokine, and chemokine levels, as well as antigen-specific cellular responses in patients with progressive, stable, and cured alveolar echinococcosis: A 10-year follow-up PloS Neglected Tropical Diseases, 2022-02-02;16(2):e0010099. 2022-02-02 [PMID: 35108275] (Human)
• R Pohl, S Feder, EM Haberl, L Rein-Fisch, TS Weiss, M Spirk, A Bruckmann, N McMullen, CJ Sinal, C Buechler Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis Biomedicines, 2022-01-07;10(1):. 2022-01-07 [PMID: 35052810] (Human)
• RLF Galvão, GC Meneses, MCC Pinheiro, AMC Martins, EF Daher, FSM Bezerra Kidney injury biomarkers and parasitic loads of Schistosoma mansoni in a highly endemic area in northeastern Brazil Acta tropica, 2022-01-14;0(0):106311. 2022-01-14 [PMID: 35038425] (Human)
• J Jhun, HS Na, KH Cho, J Kim, YM Moon, SY Lee, JS Lee, AR Lee, SJ Kim, ML Cho, SH Park A green-lipped mussel reduces pain behavior and chondrocyte inflammation and attenuated experimental osteoarthritis progression PLoS ONE, 2021-12-02;16(12):e0259130. 2021-12-02 [PMID: 34855756] (Human)
• A Riley, H Jones, J England, D Kuvshinov, V Green, J Greenman Identification of soluble tissue-derived biomarkers from human thyroid tissue explants maintained on a microfluidic device Oncology Letters, 2021-09-13;22(5):780. 2021-09-13 [PMID: 34594421] (Human)
• P Jiang, Y Zhang, B Ru, Y Yang, T Vu, R Paul, A Mirza, G Altan-Bonn, L Liu, E Ruppin, L Wakefield, KW Wucherpfen Systematic investigation of cytokine signaling activity at the tissue and single-cell levels Nature methods, 2021-09-30;18(10):1181-1191. 2021-09-30 [PMID: 34594031] (Human)
• L Kandilogia, E Filidou, I Drygiannak, G Tarapatzi, S Didaskalou, M Koffa, K Arvanitidi, G Bamias, V Valatas, V Paspaliari, G Kolios Development of a Human Intestinal Organoid Model for In Vitro Studies on Gut Inflammation and Fibrosis Stem Cells International, 2021-07-27;2021(0):9929461. 2021-07-27 [PMID: 34354753] (Human)
• Y Hosokawa, I Hosokawa, K Ozaki Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells Mediators of Inflammation, 2021-07-10;2021(0):5535844. 2021-07-10 [PMID: 34335088] (Human)
• E Jover, L Matilla, M Garaikoetx, A Fernández-, P Muntendam, F Jaisser, P Rossignol, N López-Andr Beneficial Effects of Mineralocorticoid Receptor Pathway Blockade against Endothelial Inflammation Induced by SARS-CoV-2 Spike Protein Biomedicines, 2021-06-03;9(6):. 2021-06-03 [PMID: 34204890] (Human)
• A Schaffert, L Krieg, J Weiner, R Schlichtin, E Ueberham, I Karkossa, M Bauer, K Landgraf, KM Junge, M Wabitsch, J Lehmann, BI Escher, AC Zenclussen, A Körner, M Blüher, JT Heiker, M von Bergen, K Schubert Alternatives for the worse: Molecular insights into adverse effects of bisphenol a and substitutes during human adipocyte differentiation Environment international, 2021-06-27;156(0):106730. 2021-06-27 [PMID: 34186270] (Human)
• YC Hu, IJ Tsai, HY Hsu, BL Chiang, YH Yang Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production Arthritis Research & Therapy, 2021-06-16;23(1):171. 2021-06-16 [PMID: 34134755] (Human)
• LG Lima, S Ham, H Shin, EPZ Chai, ESH Lek, RJ Lobb, AF Müller, S Mathivanan, B Yeo, Y Choi, BS Parker, A Möller Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Nature Communications, 2021-06-10;12(1):3543. 2021-06-10 [PMID: 34112803] (Human)
• D Brünnert, V Kumar, V Kaushik, J Ehrhardt, KR Chahar, PK Sharma, M Zygmunt, P Goyal Thrombin impairs the angiogenic activity of extravillous trophoblast cells via monocyte chemotactic protein-1 (MCP-1): A possible link with preeclampsia Reproductive biology, 2021-05-28;21(3):100516. 2021-05-28 [PMID: 34058707] (Human)
• S Jamieson, A Mawdesley, D Deehan, J Kirby, J Holland, A Tyson-Capp Inflammatory responses to metal oxide ceramic nanopowders Scientific Reports, 2021-05-18;11(1):10531. 2021-05-18 [PMID: 34006936] (Human)
• G Ramos-Espi, Y Wang, JM Brandner, SW Schneider, C Gorzelanny Melanoma Associated Chitinase 3-Like 1 Promoted Endothelial Cell Activation and Immune Cell Recruitment International Journal of Molecular Sciences, 2021-04-10;22(8):. 2021-04-10 [PMID: 33920100] (Human)
• GK Vasileiadi, AC Lundell, Y Zhang, K Andersson, I Gjertsson, A Rudin, C Maglio Adipocytokines in Untreated Newly Diagnosed Rheumatoid Arthritis: Association with Circulating Chemokines and Markers of Inflammation Biomolecules, 2021-02-21;11(2):. 2021-02-21 [PMID: 33669910] (Human)
• Y Hosokawa, I Hosokawa, K Ozaki, T Matsuo The Polymethoxy Flavonoid Sudachitin Inhibits Interleukin-1&beta-Induced Inflammatory Mediator Production in Human Periodontal Ligament Cells BioMed Research International, 2021-01-28;2021(0):8826586. 2021-01-28 [PMID: 33575345] (Human)
• JHS Gomes, UC Mbiakop, RL Oliveira, JR Stehmann, RM Pádua, SF Cortes, FC Braga Polyphenol-rich extract and fractions of Terminalia phaeocarpa Eichler possess hypoglycemic effect, reduce the release of cytokines, and inhibit lipase, &alpha-glucosidase, and &alpha-amilase enzymes Journal of ethnopharmacology, 2021-01-27;271(0):113847. 2021-01-27 [PMID: 33515684] (Human)
• SK Biswas, M Mittal, E Sinha, V Singh, N Arela, B Bajaj, PK Tiwari, VM Katoch, KK Mohanty Exploring the Role of C-C Motif Chemokine Ligand-2 Single Nucleotide Polymorphism in Pulmonary Tuberculosis: A Genetic Association Study from North India Journal of Immunology Research, 2020-12-16;2020(0):1019639. 2020-12-16 [PMID: 33381602] (Human)
• H Salvator, A Buenestado, M Brollo, E Naline, T Victoni, E Longchamp, H Tenor, S Grassin-De, P Devillier Clinical Relevance of the Anti-inflammatory Effects of Roflumilast on Human Bronchus: Potentiation by a Long-Acting Beta-2-Agonist Frontiers in Pharmacology, 2020-12-08;11(0):598702. 2020-12-08 [PMID: 33363471] (Human)
• R Kolahdouz-, F Shidfar, S Khodaverdi, T Arablou, S Heidari, N Rashidi, AA Delbandi Resveratrol treatment reduces expression of MCP-1, IL-6, IL-8 and RANTES in endometriotic stromal cells Journal of Cellular and Molecular Medicine, 2020-12-15;0(0):. 2020-12-15 [PMID: 33325132] (Human)
• A Pemmari, T Leppänen, M Hämäläinen, T Moilanen, K Vuolteenah, E Moilanen Widespread regulation of gene expression by glucocorticoids in chondrocytes from patients with osteoarthritis as determined by RNA-Seq Arthritis Res Ther, 2020-11-17;22(1):271. 2020-11-17 [PMID: 33203447] (Human)
• LM Moreira, A Takawale, M Hulsurkar, DA Menassa, A Antanavici, SK Lahiri, N Mehta, N Evans, C Psarros, P Robinson, AJ Sparrow, MA Gillis, N Ashley, P Naud, J Barallobre, K Theofilato, A Lee, M Norris, MV Clarke, PK Russell, B Casadei, S Bhattachar, JD Zajac, RA Davey, M Sirois, A Mead, A Simmons, M Mayr, R Sayeed, G Krasopoulo, C Redwood, KM Channon, JC Tardif, XHT Wehrens, S Nattel, S Reilly Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia Nature, 2020-11-04;0(0):. 2020-11-04 [PMID: 33149301] (Human)
• T Peeters, S Martens, V D'Onofrio, MHT Stappers, JCH van der Hi, B Houben, R Achten, LAB Joosten, IC Gyssens An observational study of innate immune responses in patients with acute appendicitis Sci Rep, 2020-10-15;10(1):17352. 2020-10-15 [PMID: 33060696] (Human)
• AER Oliveira, MCA Pereira, AT Belew, LRP Ferreira, LMN Pereira, EGA Neves, MDCP Nunes, BA Burleigh, WO Dutra, NM El-Sayed, RT Gazzinelli, SMR Teixeira Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi�strains unveil a role for fibroblasts in neutrophil recruitment and activation PLoS Pathog., 2020-08-18;16(8):e1008781. 2020-08-18 [PMID: 32810179] (Human)
• LX Heinz, J Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, A César-Razq, P Essletzbic, U Goldmann, A Stefanovic, JW Bigenzahn, S Scorzoni, MD Pizzagalli, A Bensimon, AC Müller, FJ King, J Li, E Girardi, ML Mbow, CE Whitehurst, M Rebsamen, G Superti-Fu TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9 Nature, 2020-05-13;581(7808):316-322. 2020-05-13 [PMID: 32433612] (Human)
• YH Wang, FM Suk, CL Liu, TL Chen, YC Twu, MH Hsu, YJ Liao Antifibrotic Effects of a Barbituric Acid Derivative on Liver Fibrosis by Blocking the NF-&kappaB Signaling Pathway in Hepatic Stellate Cells Front Pharmacol, 2020-03-31;11(0):388. 2020-03-31 [PMID: 32296336] (Human)
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• Receptor-Type Protein-Tyrosine Phosphatase ? and Colony Stimulating Factor-1 Receptor in the Intestine: Cellular Expression and Cytokine- and Chemokine Responses by Interleukin-34 and Colony Stimulating Factor-1 PLoS ONE, 2016-11-29;11(11):e0167324. 2016-11-29 [PMID: 27898738] (Human)
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• Fjeldborg K, Pedersen S, Moller H, Christiansen T, Bennetzen M, Richelsen B Human adipose tissue macrophages are enhanced but changed to an anti-inflammatory profile in obesity. J Immunol Res, 2014-03-11;2014(0):309548. 2014-03-11 [PMID: 24741586] (Human)
• Zughaier , Susu M, Kandler , Justin L, Shafer , William Neisseria gonorrhoeae modulates iron-limiting innate immune defenses in macrophages. PLoS ONE, 2014-01-28;9(1):e87688. 2014-01-28 [PMID: 24489950] (Human)
• Cheng K, Wong S, Linn Y, Ho L, Chng W, Schwarz H CD137 ligand signalling induces differentiation of primary acute myeloid leukaemia cells. Br J Haematol, 2014-01-15;165(1):134-44. 2014-01-15 [PMID: 24428589] (Human)
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• Ding C, Wilding J, Bing C 1,25-dihydroxyvitamin D3 protects against macrophage-induced activation of NFkappaB and MAPK signalling and chemokine release in human adipocytes. PLoS ONE, 2013-04-24;8(4):e61707. 2013-04-24 [PMID: 23637889] (Human)
• Jeffery H, Soderberg-Naucler C, Butler L Human cytomegalovirus induces a biphasic inflammatory response in primary endothelial cells. J Virol, 2013-03-27;87(11):6530-5. 2013-03-27 [PMID: 23536673] (Human)
• Fjeldborg K, Christiansen T, Bennetzen M, J Moller H, Pedersen S, Richelsen B The macrophage-specific serum marker, soluble CD163, is increased in obesity and reduced after dietary-induced weight loss. Obesity (Silver Spring), 2013-07-02;21(12):2437-43. 2013-07-02 [PMID: 23512476] (Human)
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• Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse. J Neuroinflammation, 2012-08-18;9(0):203. 2012-08-18 [PMID: 22901451] (Human)
• Singh S, Wu T Urine VCAM-1 as a marker of renal pathology activity index in lupus nephritis. Oncogene, 2012-07-13;14(4):R164. 2012-07-13 [PMID: 22788914] (Human)
• Neuenschwander LC, Bittencourt H, Ribeiro AF, Teixeira AL, Teixeira MM, Teixeira JC, Nobre V Plasma levels of procalcitonin and eight additional inflammatory molecules in febrile neutropenic patients. Clinics (Sao Paulo), 2011-01-01;66(10):1699-705. 2011-01-01 [PMID: 22012040] (Human)
• Toti P, Arcuri F, Tang Z, Schatz F, Zambrano E, Mor G, Niven-Fairchild T, Abrahams VM, Krikun G, Lockwood CJ, Guller S Focal increases of fetal macrophages in placentas from pregnancies with histological chorioamnionitis: potential role of fibroblast monocyte chemotactic protein-1. Am. J. Reprod. Immunol., 2010-11-19;65(5):470-9. 2010-11-19 [PMID: 21087336] (Human)
• Rodland EK, Ueland T, Pedersen TM, Halvorsen B, Muller F, Aukrust P, Froland SS Activation of platelets by Aspergillus fumigatus and potential role of platelets in the immunopathogenesis of Aspergillosis. Infect. Immun., 2009-12-14;78(3):1269-75. 2009-12-14 [PMID: 20008537] (Human)
• Ockinger J, Stridh P, Beyeen AD, Lundmark F, Seddighzadeh M, Oturai A, Sorensen PS, Lorentzen AR, Celius EG, Leppa V, Koivisto K, Tienari PJ, Alfredsson L, Padyukov L, Hillert J, Kockum I, Jagodic M, Olsson T Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis. Genes Immun., 2009-10-29;11(2):142-54. 2009-10-29 [PMID: 19865101] (Human)
• Kurago ZB, Lam-ubol A, Stetsenko A Lipopolysaccharide-squamous cell carcinoma-monocyte interactions induce cancer-supporting factors leading to rapid STAT3 activation. Head Neck Pathol, 2008-03-01;2(1):1-12. 2008-03-01 [PMID: 19603082] (Human)
• Li Z, Alam S, Wang J, Sandstrom CS, Janciauskiene S, Mahadeva R Oxidized alpha1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema. Am. J. Physiol. Lung Cell Mol. Physiol., 2009-06-12;297(2):L388-400. 2009-06-12 [PMID: 19525388] (Human)
• Tam FW, Riser BL, Meeran K, Rambow J, Pusey CD, Frankel AH Urinary monocyte chemoattractant protein-1 (MCP-1) and connective tissue growth factor (CCN2) as prognostic markers for progression of diabetic nephropathy. Cytokine, 2009-05-05;47(1):37-42. 2009-05-05 [PMID: 19409809] (Human)
• Brietzke E, Kauer-Sant'Anna M, Teixeira AL, Kapczinski F Abnormalities in serum chemokine levels in euthymic patients with bipolar disorder. Brain Behav. Immun., 2009-05-04;23(8):1079-82. 2009-05-04 [PMID: 19406226] (Human)
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• Rebelo SL, Amel-Kashipaz MR, Radford PM, Bainbridge SE, Fiets R, Fang J, McDermott EM, Powell RJ, Todd I, Tighe PJ Novel markers of inflammation identified in tumor necrosis factor receptor-associated periodic syndrome (TRAPS) by transcriptomic analysis of effects of TRAPS-associated tumor necrosis factor receptor type I mutations in an endothelial cell line. Arthritis Rheum., 2009-01-01;60(1):269-80. 2009-01-01 [PMID: 19116900] (Human)
• Weigt SS, Elashoff RM, Keane MP, Strieter RM, Gomperts BN, Xue YY, Ardehali A, Gregson AL, Kubak B, Fishbein MC, Saggar R, Ross DJ, Lynch JP, Zisman DA, Belperio JA Altered levels of CC chemokines during pulmonary CMV predict BOS and mortality post-lung transplantation. Am. J. Transplant., 2008-07-01;8(7):1512-22. 2008-07-01 [PMID: 18513272] (Human)
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• Teixeira AL, Reis HJ, Nicolato R, Brito-Melo G, Correa H, Teixeira MM, Romano-Silva MA Increased serum levels of CCL11/eotaxin in schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2007-11-23;32(3):710-4. 2007-11-23 [PMID: 18096286] (Human)
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• Wu T, Xie C, Wang HW, Zhou XJ, Schwartz N, Calixto S, Mackay M, Aranow C, Putterman C, Mohan C Elevated urinary VCAM-1, P-selectin, soluble TNF receptor-1, and CXC chemokine ligand 16 in multiple murine lupus strains and human lupus nephritis. J. Immunol., 2007-11-15;179(10):7166-75. 2007-11-15 [PMID: 17982109] (Human)
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Bioinformatics

• Gene Symbol: CCL2