Human CCL14a/HCC-1 DuoSet ELISA, 15 Plate

Images

 

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Human CCL14a/HCC-1 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
CCL14

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY1578.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CCL14a/HCC-1 DuoSet ELISA, 15 Plate

  • CCL14
  • CCL14a
  • HCC1
  • HCC-1

Background

CCL14, is a member of the chemokine superfamily of ligands. In-depth genome analysis has determined that there is no mouse ortholog for human CCL14. Two alternatively spliced isoforms of CCL14, CCL14a/HCC-1 and CCL14b/HHC-3, have been identified. The CCL14a/HCC-1 isoform is a 93 amino acid (aa) precursor peptide with a predicted molecular weight of 10 kDa, while the CCL14b/HCC-3 isoform contains an additional 17 aa insertion and has a predicted molecular weight of 12 kDa. CCL14a/HCC-1 is cleaved into a 74 aa secreted bioactive peptide by Plasmin or u-Plasminogen Activator/Urokinase. CCL14a/HCC-1 binds and activates CCR1, CCR3, and CCR5; it also binds the non-signaling chemokine decoy receptors DARC and D6. CCL14a/HCC-1 is widely expressed in normal tissues including spleen, liver, skeletal and heart muscle, gut, and bone marrow, and it circulates at high concentrations in the plasma. CCL14a/HCC-1 induces the chemotaxis of T lymphocytes, monocytes, and eosinophils. It also exhibits anti-HIV activities by causing CCR5, a key mediator of HIV entry, internalization and intracellular sequestration.

Customers Who Viewed This Item Also Viewed...

MAB363
Species: Hu
Applications: ELISA(Cap), ELISA(Det), ELISA(Sta), Neut, WB
MAB145
Species: Hu
Applications: CyTOF-ready, Flow
MAB182
Species: Hu
Applications: CyTOF-ready, Flow, ICC, Neut
MAB328
Species: Hu
Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), IHC, ICFlow, Neut, WB
MAB155
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut
DRN00B
Species: Hu
Applications: ELISA
DCC700
Species: Hu
Applications: ELISA
MAB208
Species: Hu
Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), ICC, ICFlow, Neut, Simple Western, WB
DCP00
Species: Hu
Applications: ELISA
508-CK/CF
Species: Hu
Applications: BA, BA
NBP2-46256
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
NBP2-45937
Species: Hu
Applications: IHC, WB
DY394
Species: Hu
Applications: ELISA
DY281
Species: Hu
Applications: ELISA
MMA00
Species: Mu
Applications: ELISA
NBP2-67471
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NBP1-32914
Species: Hu, Mu
Applications: ICC/IF, IHC, WB
NBP2-50037
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, KO, WB
AF1180
Species: Hu
Applications: ICC, IHC, Simple Western, WB

Publications for CCL14a/HCC-1 (DY1578)(2)

Reviews for CCL14a/HCC-1 (DY1578) (0)

There are no reviews for CCL14a/HCC-1 (DY1578). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CCL14a/HCC-1 (DY1578) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Review this Product

Be the first to review our Human CCL14a/HCC-1 DuoSet ELISA, 15 Plate and receive a gift card or discount.

Bioinformatics

Gene Symbol CCL14