Human B7-H6 DuoSet ELISA, 5 Plate

Name: Human B7-H6 DuoSet ELISA, 5 Plate
Brand: Novus Biologicals
SKU: DY7144-05
Price: 450 USD
Availability: InStock

(1 Publication)

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Summary

Reactivity	HuSpecies Glossary
Applications	ELISA
Conjugate	Biotin

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Human B7-H6 DuoSet ELISA, 5 Plate Summary

Source	N/A
Assay Type	Solid Phase Sandwich ELISA
Inter-Assay	See PDF Datasheet for details
Intra-Assay	See PDF Datasheet for details
Spike Recovery	See PDF Datasheet for details
Sample Volume	See PDF Datasheet for details

Applications/Dilutions

Dilutions

ELISA

Application Notes

No significant interference observed with available related molecules.

Publications

Read Publication using DY7144-05.

Packaging, Storage & Formulations

Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human B7-H6 DuoSet ELISA, 5 Plate

B7 homolog 6
B7H6
B7-H6
DKFZp686I21167
DKFZp686O24166
NCR3LG1

Background

B7-H6 is a transmembrane immune regulatory protein that binds to NKp30 expressed on NK cells. Ligation of NKp30 by B7-H6 induces NK cell activation and target cell cytolysis. B7-H6 is expressed on a wide range of hematopoietic, carcinoma, and melanoma tumor cells. The expression of NKp30 ligands on tumor cells correlates with tumor cell sensitivity to NKp30-dependent cell lysis.

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Human B7-H6 DuoSet
ELISA, 5 Plate

DY7144-05

Species: Hu

Applications: ELISA

Publications for B7-H6 (DY7144-05)(1)

We have publications tested in 1 confirmed species: Human.

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Publication using DY7144-05	Applications	Species
Silvia Pesce, Valerio Belgrano, Marco Greppi, Simona Carlomagno, Margherita Squillario, Annalisa Barla et al. Different Features of Tumor-Associated NK Cells in Patients With Low-Grade or High-Grade Peritoneal Carcinomatosis Frontiers in Immunology 2019-08-21 [PMID: 31497016] (Human)		Human

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CD4+NKG2D+ T cells exert pro-migratory, cytolytic and pro-inflammatory properties.(A) Flow cytometry: The dot plot shows a representative example of NKG2D expression on CD3+CD4+CD8-CD56− T cells derived from the peripheral blood of a healthy donor (HD). The bar graph represents the mean frequency of CD4+NKG2D+ T cells in the peripheral blood of HDs (n = 20), stable RRMS (n = 15) and active RRMS patients (n = 14). (B–E) Mean fluorescence intensity (MFI) of different markers indicative for migratory capacity (B), activation (C), or cytolytic capacity (D, E) of CD4+NKG2D+ and CD4+NKG2D− T cells from the peripheral blood of HDs (n = 6) or active RRMS patients (n = 6). (F) Percentages of naive (CD45RA+CD62L+), T central memory (Tcm, CD45RA-CD62L+), T effector memory (Tem, CD45RA-CD62L−) and T effector memory RA (Tem-RA, CD45RA+CD62L-) cells in the CD4+NKG2D+ and CD4+NKG2D− T cell compartment assessed by flow cytometry (n = 6 HDs). (G) Carboxyfluorescein succinimidyl ester (CFSE) proliferation assays of CD4+NKG2D+ T cells and CD4+NKG2D− T cells under CD3/CD28, CD3/NKG2D, MOG35-55 (10 µg/ml or 100 µg/ml), MBP1-11 or PLP190-209 stimulation (n = 8 HDs). (H) Intracellular cytokine staining for IFN-gamma and IL-17 of CD4+NKG2D+ and CD4+NKG2D− T cells derived from the peripheral blood of HDs (n = 7). The dot plots depict a representative example of IFN-gamma - and IL-17-positive cells upon CD3/CD28 stimulation. The bar graphs show the frequencies of IFN-gamma or IL-17 positive cells of unstimulated, CD3/CD28- or CD3/NKG2D-stimulated cells. (I) Comparison of the proportions of IFN-gamma or IL-17 positive CD3/CD28-stimulated CD4NKG2D+ T cells derived from frozen PBMCs of HDs (n = 6) or active RRMS patients (n = 6). *P < 0.05. ns, not significant; unstim., unstimulated. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/24282598), licensed under a CC-BY license. Not internally tested by R&D Systems.

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The expression of PD-1 on CD4+T cells CD8+T cells and CD56+NK cells in silicosis. a Gating strategy and expression profiles of PD-1 in peripheral CD4+T cells CD8+T cells and CD56+NK cells in TB group, SILs group, SILs&LTBI group TB&SILs-P group and TB&SILs-N group. b The expression of PD-1 on CD4+T cells in TB group, SILs group, SILs&LTBI group TB&SILs-P group and TB&SILs-N group; c The expression of PD-1 on CD8+T cells in TB group, SILs group, SILs&LTBI group TB&SILs-P group and TB&SILs-N group; d The expression of PD-1 on CD56+NK cells in TB group, SILs group, SILs&LTBI group TB&SILs-P group and TB&SILs-N group; e Analyzed the correlation between the level of IFN-gamma and expression of PD-1 on CD4+T cells; f Analyzed the correlation between the level of IFN-gamma and expression of PD-1 on CD8+T cells; g Analyzed the correlation between the level of IFN-gamma and expression of PD-1 on CD56+NK cells. *p AF1086) at 1ug/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-goat IgG VisUCyte HRP Polymer Antibody (Catalog # VC004) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to cell surface.

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Human B7-H6 DuoSet ELISA, 5 Plate

Species Glossary

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Human B7-H6 DuoSet ELISA, 5 Plate Summary

Applications/Dilutions

Packaging, Storage & Formulations

Notes

Alternate Names for Human B7-H6 DuoSet ELISA, 5 Plate

Background

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Publications for B7-H6 (DY7144-05)(1)

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