HspBP1 Antibody - BSA Free

Western Blot: HspBP1 Antibody [NBP2-49658] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10Lane 2: Human cell line RT-4Lane 3: Human cell line U-251 MG

Immunohistochemistry-Paraffin: HspBP1 Antibody [NBP2-49658] - Staining of human pancreas shows low expression as expected.

Immunohistochemistry: HspBP1 Antibody [NBP2-49658] - Staining of human testis shows strong cytoplasmic and nuclear positivity in testis.

Immunohistochemistry-Paraffin: HspBP1 Antibody [NBP2-49658] - Staining in human testis and pancreas tissues using anti-HSPBP1 antibody. Corresponding HSPBP1 RNA-seq data are presented for the same tissues.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

HspBP1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit HspBP1 Antibody - BSA Free (NBP2-49658) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against a recombinant protein corresponding to amino acids: KLKVKSAFLLQNLLVGHPEHKGTLCSMGMVQQLVALVRTEHSPFHEHVLGALCSLVTDFPQGVRECREPELGLEELLRHRCQLLQQHEEYQEELEFCEKLLQT
• Predicted Species: Mouse (99%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HSPBP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  HspBP1 Recombinant Protein Antigen (NBP2-49658PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for HspBP1 Antibody - BSA Free

• FES1
• Heat shock protein-binding protein 1
• Hsp70 binding protein 1
• hsp70 interacting protein
• hsp70-binding protein 1
• Hsp70-binding protein 2
• Hsp70-interacting protein 1
• Hsp70-interacting protein 2
• HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
• HSPBP
• HspBP1
• hspBP2

Background

Heat shock protein binding protein is an Hsp70-interacting protein that was first isolated from a human heart cDNA library using the yeast two-hybrid system. HspBP1 binds the ATPase domain of Hsp70, and inhibits Hsp70 chaperone activity. More recently HspBP1 was found to promote nucleotide dissociation from Hsc70 and is capable of altering the confirmation of the Hsp70 ATPase domain. HspBP1 is capable of regulating any Hsp70 activity that requires ATPase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HSPBP1