HspBP1 Products

Description

Heat shock protein binding protein is an Hsp70-interacting protein that was first isolated from a human heart cDNA library using the yeast two-hybrid system. HspBP1 binds the ATPase domain of Hsp70, and inhibits Hsp70 chaperone activity. More recently HspBP1 was found to promote nucleotide dissociation from Hsc70 and is capable of altering the confirmation of the Hsp70 ATPase domain. HspBP1 is capable of regulating any Hsp70 activity that requires ATPase.

Bioinformatics

Entrez	23640 Human
Uniprot	AAH01236 Human NM_012267 Human NP_001123578 Human NP_036399.3 Human Q9NZL4 Human
Product By Gene ID	23640
Alternate Names	FES1 Heat shock protein-binding protein 1 Hsp70 binding protein 1 hsp70 interacting protein hsp70-binding protein 1 Hsp70-binding protein 2 Hsp70-interacting protein 1 Hsp70-interacting protein 2 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 HSPBP HspBP1 hspBP2 HspBP2

Research Areas for HspBP1

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Signal Transduction