HLA-DR Antibody (TAL 1B5)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, RIA, CyTOF-ready
Clone
TAL 1B5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

HLA-DR Antibody (TAL 1B5) Summary

Immunogen
Bristol 8 separated alpha chain preparation
Localization
Type I membrane protein
Specificity
Specific for Human Leukocyte Antigen DR, alpha subunit. May be used for HLA typing.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HLA-DRA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100 - 1:2000
  • ELISA 1:100 - 1:2000
  • Flow Cytometry 1:10 - 1:1000
  • Immunocytochemistry/Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry 1:10 - 1:500
  • Radioimmunoassay 1:100 - 1:2000
  • CyTOF-ready
Application Notes
TAL 1B5 can detect both dimers and the DR alpha chain by western blot. This antibody is CyTOF ready.
Theoretical MW
33 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using NB600-989.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for HLA-DR Antibody (TAL 1B5)

  • FLJ51114
  • histocompatibility antigen HLA-DR alpha
  • HLA class II histocompatibility antigen, DR alpha chain
  • HLADR
  • HLA-DR
  • HLA-DRA
  • HLA-DRA1
  • major histocompatibility complex, class II, DR alpha
  • MHC cell surface glycoprotein
  • MHC class II antigen DRA
  • MHC Class II DR
  • MLRW

Background

HLA DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of an alpha chain (36 kDa) and a beta chain (27 kDa). It is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T helper cells. They therefore have a critical role in the initiation of the immune response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for HLA-DR Antibody (NB600-989)(1)


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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for HLA-DR Antibody (NB600-989) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NB600-989AF350
Alexa Fluor 405 NB600-989AF405
Alexa Fluor 488 NB600-989AF488
Alexa Fluor 532 NB600-989AF532
Alexa Fluor 532 NB600-989AF532
Alexa Fluor 594 NB600-989AF594
Alexa Fluor 647 NB600-989AF647
Alexa Fluor 700 NB600-989AF700
Alexa Fluor 750 NB600-989AF750
Allophycocyanin/Cy7 NB600-989APCCY7
Biotin NB600-989B
DyLight 350 NB600-989UV
DyLight 405 NB600-989V
DyLight 488 NB600-989G
DyLight 550 NB600-989R
DyLight 594 NB600-989DL594
DyLight 650 NB600-989C
DyLight 680 NB600-989FR
DyLight 755 NB600-989IR
FITC NB600-989F
HRP NB600-989H
Janelia Fluor 549 NB600-989JF549
Janelia Fluor 646 NB600-989JF646
PE/Atto594 NB600-989PEATT594
PE/Cy5.5 NB600-989PECY55
PE/Cy7 NB600-989PECY7

Additional HLA-DR Products

Array NB600-989

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Contact Information

Learn the difference between western blot and simple western

Product PDFs

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Bioinformatics

Gene Symbol HLA-DRA
Entrez