HLA-DR Antibody (TAL 1B5)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, RIA, CyTOF-ready
Clone
TAL 1B5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

HLA-DR Antibody (TAL 1B5) Summary

Immunogen
Bristol 8 separated alpha chain preparation
Localization
Type I membrane protein
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HLA-DRA
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100 - 1:2000
  • ELISA 1:100 - 1:2000
  • Flow Cytometry 1:10 - 1:1000
  • Immunocytochemistry/Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry 1:10 - 1:500
  • Radioimmunoassay 1:100 - 1:2000
  • CyTOF-ready
Application Notes
TAL 1B5 can detect both dimers and the DR alpha chain by western blot.
Theoretical MW
33 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for HLA-DR Antibody (TAL 1B5)

  • FLJ51114
  • histocompatibility antigen HLA-DR alpha
  • HLA class II histocompatibility antigen, DR alpha chain
  • HLADR
  • HLA-DR
  • HLA-DRA
  • HLA-DRA1
  • major histocompatibility complex, class II, DR alpha
  • MHC cell surface glycoprotein
  • MHC class II antigen DRA
  • MHC Class II DR
  • MLRW

Background

HLA DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of an alpha chain (36 kDa) and a beta chain (27 kDa). It is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T helper cells. They therefore have a critical role in the initiation of the immune response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for HLA-DR Antibody (NB600-989) (0)

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Secondary Antibodies

 

Isotype Controls

Additional HLA-DR Products

HLA-DR NB600-989

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Bioinformatics

Gene Symbol HLA-DRA
Entrez