HLA-DR Products



The L243 monoclonal antibody reacts with the HLA-DR antigen, a member of MHC class II molecules. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD alpha (heavy) chain and a 27 kD beta (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. L243 has been reported to block mixed lymphocyte reactions.


Entrez Human
Uniprot Human
Product By Gene ID 3122
Alternate Names
  • MHC cell surface glycoprotein
  • FLJ51114
  • HLA class II histocompatibility antigen, DR alpha chain
  • MHC class II antigen DRA
  • histocompatibility antigen HLA-DR alpha
  • HLA-DRA1
  • MLRW
  • major histocompatibility complex, class II, DR alpha

Research Areas for HLA-DR

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cell Biology
Diabetes Research

Bioinformatics Tool for HLA-DR

Discover related pathways, diseases and genes to HLA-DR. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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