HLA Class I Antibody (MEM-123) [Allophycocyanin]

• Reactivity: Hu, Bv, Pm
• Applications: ELISA, Flow, IP, CyTOF-ready
• Clone: MEM-123
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

HLA Class I Antibody (MEM-123) [Allophycocyanin] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: COS-7 African green monkey kidney cells
• Specificity: This antibody (clone MEM-123) reacts with all human classical MHC Class I molecules (major histocompatibility complex) in native cell-surface forms as well as with human HLA-G cDNA transfected cells. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. This antibody completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-blocks This antibody MEM-G/9.
• Isotype: IgG3
• Clonality: Monoclonal
• Host: Mouse
• Gene: HLA-A
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • ELISA
  • Flow Cytometry
  • Immunoprecipitation
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB500-505. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Alternate Names for HLA Class I Antibody (MEM-123) [Allophycocyanin]

• A-10 alpha chain
• FLJ26655
• HLA class I histocompatibility antigen, A-1 alpha chain
• HLA class I histocompatibility antigen, A-28 alpha chain
• HLA class I histocompatibility antigen, A-9 alpha chain
• HLA Class I
• HLAA
• HLA-A
• HLA-ABC
• major histocompatibility complex, class I, A
• MHC class I antigen A*1
• MHC class I antigen A*11
• MHC class I antigen A*80

Background

HLA CLass I is involved in the presentation of foreign antigens to the immune system. This antibody is a valuable reagent for analysing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders. This antibody is also suitable as a positive control for HLA tissue typing and crossmatching.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HLA-A
• Entrez:
  • 3106(Human)
  • 3107(Human)