HEXO Antibody - BSA Free

Immunohistochemistry: HEXO Antibody - BSA Free [NBP3-46554] - Immunohistochemistry of paraffin-embedded human testis using (HEXO antibody) at dilution of 1:50

Western Blot: HEXO Antibody - BSA Free [NBP3-46554] - K-562 cells were subjected to SDS PAGE followed by western blot with (HEXO antibody) at dilution of 1:1000

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

HEXO Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit HEXO Antibody - BSA Free (NBP3-46554) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: exoribonuclease 1. (Uniprot# Q8IV48)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ERI1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:20-1:200
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 46 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for HEXO Antibody - BSA Free

• 3' exoribonuclease
• 3'-5' exonuclease ERI1
• 3'EXO
• 3'HEXO
• EC 3.1
• enhanced RNAi three prime mRNA exonuclease homolog 1
• Eri-1 homolog
• exoribonuclease 1
• HEXO
• histone mRNA 3' end-specific exonuclease
• Histone mRNA 3'-end-specific exoribonuclease
• Histone mRNA 3'-exonuclease 1
• MGC35395
• Protein 3'hExo
• THEX1
• three prime histone mRNA exonuclease 1,3'-5' exoribonuclease 1
• three prime mRNA exonuclease 1

Background

HEXO is a 50-kD protein containing a SAP domain capable of recognizing AT-rich scaffold-attachment regions (SARs) in chromosomal DNA, and a exonuclease domain similar to those of DEDD exonuclease family members. HEXO is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as a regulator of RNA interference (RNAi).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ERI1