HERPUD1 Antibody Pair

Product Discontinued

HERPUD1 Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: mouse monoclonal anti-HERPUD1 (300 ug)
• Antibody pair for WB: rabbit polyclonal anti-HERPUD1 (50 ul)
• Clonality: Polyclonal
• Gene: HERPUD1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HERPUD1 Antibody Pair

• HERPMIF1
• homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-likedomain member 1 protein
• homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-likedomain member 1
• homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domainmember 1 protein
• KIAA0025MMS-inducible
• Methyl methanesulfonate (MMF)-inducible fragment protein 1
• Mif1
• SUP

Background

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: HERPUD1