Hemoglobin beta Antibody (1G8) [Janelia Fluor® 549] - Chimeric

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clone
1G8
Clonality
Monoclonal
Host
Rabbit
Conjugate
Janelia Fluor 549

Order Details

Hemoglobin beta Antibody (1G8) [Janelia Fluor® 549] - Chimeric Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
The original antibody was generated by immunizing BALB/c mice with synthetic N-terminal glycopeptide (VHLTPEC) and KLH conjugate. (Uniprot# P68871)
Specificity
This antibody binds human hemoglobin glycated at the N-terminal valine of the hemoglobin beta chain and does not cross react with non-glycated hemoglobin.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
HBB
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Hemoglobin beta Antibody (1G8) [Janelia Fluor® 549] - Chimeric

  • beta globin chain
  • beta-globin
  • CD113t-C
  • HBBB
  • HBD
  • Hemoglobin beta chain
  • hemoglobin subunit beta
  • hemoglobin, beta

Background

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HBB