HAP40 Antibody

Western Blot: HAP40 Antibody [NB300-163] - Analysis of HAP40 in mouse brain using NB300-163 at 1:500 dilution. Co-Immunoprecipitates Huntingtin protein (350 kDa) [not shown on blot].

Product Discontinued

HAP40 Antibody Summary

• Immunogen: A partial peptide made to the 40 kDa mouse HAP40 protein
• Specificity: This reacts with residues 314-325 [DGHGQDTSGQLP] of the mouse HAP40 protein (co-immunopreciptates Huntingtin protein).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: F8A1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:1000
• Application Notes: Western blot
• Control:

  Mouse Brain Whole Tissue Lysate (Adult Whole Normal)

Reactivity Notes

Mouse. Other species have not been tested.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for HAP40 Antibody

• coagulation factor VIII-associated (intronic transcript) 1
• coagulation factor VIII-associated 1
• cpG island protein
• DXS522E
• F8A
• factor VIII associated protein
• factor VIII intron 22 protein
• HAP40
• huntingtin-associated protein 40

Background

HAP40 is a 40 kDa Huntington-associated protein. It is likely to contribute to the function of normal Huntington and is a candidate for involvement in the aberrant nuclear localization of mutant Huntington, found in degenerating neurons of Huntingtons disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: F8A1
• Entrez:
  • 8263(Human)
  • 14070(Mouse)