Hairless Antibody [DyLight 594]

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 594

Hairless Antibody [DyLight 594] Summary

• Immunogen: E. coli-derived recombinant human Hairless
  Met1-Thr277
  Accession # O43593
• Specificity: Detects human Hairless in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: HR
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Hairless Antibody [DyLight 594]

• ALUNC
• AU
• AUHSA277165
• FLJ98880
• hairless (mouse) homolog
• hairless homolog (mouse)
• Hairless
• HR
• MUHH
• MUHH1
• protein hairless

Background

HR (hairless) is 1189 amino acids long, weighing approximately 127 kDa, with a short isomer that is 1134 amino acids long, weighing approximately 122 kDa. HR functions as a transcription factor that regulates the phases of hair growth, with strong expressions in the small intestine and the skin (for isoform 2 only), and weak expressions in the brain and colon. Current studies are being done on several diseases and disorders including atrichia with popular lesions, hypotrichosis, thyroiditis, and autosomal recessive diseases. HR has also been shown to have interactions with VDR, ESR2, RARA, TBL1X, and HDAC1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HR