HABP2 Antibody

Immunohistochemistry-Paraffin: HABP2 Antibody [NBP1-83419] - Staining of human small intestine shows strong intracellular proteinaceous material positivity in glandular cells.

Product Discontinued

HABP2 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: GHCALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGI
• Predicted Species: Mouse (91%), Rat (92%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HABP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reactivity Notes

Reactivity reported in scientific literature (PMID: 24743550)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for HABP2 Antibody

• EC 3.4.21
• EC 3.4.21.-
• EC 3.4.21.4
• EC 3.4.21.92
• Factor seven-activating protease
• Factor VII-activating protease
• FSAPfactor VII activating protein
• HABP
• Hepatocyte growth factor activator-like protein
• HGFALhyaluronic acid binding protein 2
• hyaluronan binding protein 2
• hyaluronan-binding protein 2
• PHBPplasma hyaluronan binding protein
• Plasma hyaluronan-binding protein

Background

HABP2 is encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HABP2 Antibody (NBP1-83419)(1)

Publication using NBP1-83419

• Bachmann J, Burte F, Pramana S et al. Affinity Proteomics Reveals Elevated Muscle Proteins in Plasma of Children with Cerebral Malaria. PLoS Pathog 2014-04-01 [PMID: 24743550]

Bioinformatics

• Gene Symbol: HABP2