Guanylyl Cyclase alpha 1 Antibody

Western Blot: Guanylyl Cyclase alpha 1 Antibody [H00002982-B01P] - Analysis of GUCY1A3 expression in transfected 293T cell line by GUCY1A3 polyclonal antibody. Lane 1: GUCY1A3 transfected lysate(75.9 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

Guanylyl Cyclase alpha 1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: GUCY1A3 (AAH28384.1, 1 a.a. - 690 a.a.) full-length human protein. MFCTKLKDLKITGECPFSLLAPGQVPNESSEEAAGSSESCKATMPICQDIPEKNIQESLPQRKTSRSRVYLHTLAESICKLIFPEFERLNVALQRTLAKHKIKESRKSLEREDFEKTIAEQAVAAGVPVEVIKESLGEEVFKICYEEDENILGVVGGTLKDFLNSFSTLLKQSSHCQEAGKRGRLEDASILCLDKEDDFLHVYYFFPKRTTSLILPGIIKAAAHVLYETEVEVSLMPPCFHNDCSEFVNQPYLLYSVHMKSTKPSLSPSKPQSSLVIPTSLFCKTFPFHFMFDKDMTILQFGNGIRRLMNRRDFQGKPNFEEYFEILTPKINQTFSGIMTMLNMQFVVRVRRWDNSVKKSSRVMDLKGQMIYIVESSAILFLGSPCVDRLEDFTGRGLYLSDIPIHNALRDVVLIGEQARAQDGLKKRLGKLKATLEQAHQALEEEKKKTVDLLCSIFPCEVAQQLWQGQVVQAKKFSNVTMLFSDIVGFTAICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGLHKESDTHAVQIALMAVKMMELSDEVMSPHGEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCSVPRKINVSPTTYRLLKDCPGFVFTPRSREELPPNFPSEIPGICHFLDAYQQGTNSKPCFQKKDVEDGNANFLGKASGID
• Specificity: GUCY1A3 - guanylate cyclase 1, soluble, alpha 3,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: GUCY1A1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Guanylyl Cyclase alpha 1 Antibody

• EC 4.6.1.2
• GC-S-alpha-1
• GCS-alpha-1
• GCS-alpha-3
• guanylate cyclase 1, soluble, alpha 3
• guanylate cyclase soluble subunit alpha-3
• Guanylyl Cyclase alpha 1
• GUC1A3
• GUC1A3GUCA3
• GUCSA3
• GUCSA3GC-SA3
• GUCY1A1
• GUCY1A3
• Soluble guanylate cyclase large subunit

Background

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit, such as alpha-1 (GUCY1A3), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GUCY1A1
• Entrez:
  • 2982(Human)
• Uniprot:
  • AAH28384.1(Human)