GTPBP3 Antibody

Western Blot: GTPBP3 Antibody [NBP2-16765] - Sample (30 ug of whole cell lysate) A: IMR32 10% SDS PAGE diluted at 1:1000

Immunohistochemistry-Paraffin: GTPBP3 Antibody [NBP2-16765] - Paraffin-embedded human brain. GTPBP3 antibody [C1C3] dilution: 1:500.

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

GTPBP3 Antibody Summary

• Description: Novus Biologicals Rabbit GTPBP3 Antibody (NBP2-16765) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human GTPBP3. The exact sequence is proprietary.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GTPBP3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 52 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Bovine (81%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 1% BSA, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for GTPBP3 Antibody

• FLJ14700
• FLJ17836
• GTP binding protein 3 (mitochondrial)
• GTPBG3
• GTP-binding protein 3
• MSS1
• MTGP1Mitochondrial GTP-binding protein 1
• THDF1
• tRNA modification GTPase GTPBP3, mitochondrial

Background

This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: GTPBP3
• Uniprot:
  • Q969Y2(Human)