GOLGA6 Antibody

• Reactivity: Hu
• Applications: ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

GOLGA6 Antibody Summary

• Description: Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.
• Immunogen: Peptide with sequence C-TLEKADLKTTLYH corresponding to internal region according to NP_001033729.2.
• Epitope: internal region
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: GOLGA6A
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:8000
• Application Notes: WB: Preliminary experiments gave an approx. 29 kDa band in human testis lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 79.9 kDa band according to NP_001033729.2. The 29 kDa band was successfully blocked by incubation with the immunizing peptide.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GOLGA6 Antibody

• FLJ75859
• GLPGolgin-like protein
• GOLGA6Golgin linked to PML
• golgi autoantigen, golgin subfamily a, 6
• golgi autoantigen, golgin subfamily a, 6A
• golgi autoantigen, golgin subfamily a, member 6
• golgin A6 family, member A
• Golgin subfamily A member 6A

Background

GOLGA6 is a member of the golgin family of proteins, whose members localise to the Golgi appartus. This gene is found in a large, low copy repeat sequence or duplicon that is found in multiple copies, that are greater than 90% similar, on chromosome 15. Duplicons are associated with deletions, inversions and other chromosome rearrangements that underlie genomic disease. The protein encoded by this gene is thought to be a functional golgin protein while the majority of the related copies of this gene are thought to be transcribed pseudogenes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GOLGA6 Antibody (NBP1-46132)(1)

Publication using NBP1-46132

• Gilles F, Goy A, Remache Y et al. Cloning and characterization of a Golgin-related gene from the large-scale polymorphism linked to the PML gene. Genomics 2000-12-15 [PMID: 11161787]

Bioinformatics

• Gene Symbol: GOLGA6A
• Entrez:
  • 342096(Human)
• Uniprot:
  • NP_001033729.2(Human)