GMF-beta Recombinant Protein


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Product Details

Reactivity HuSpecies Glossary

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GMF-beta Recombinant Protein Summary

A recombinant protein corresponding to Human GMF-beta

Source: E. coli

E. coli

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
Reconstitution Instructions
Centrifuge prior to opening. Reconstitute with sterilized water to a final concentration of at least 0.1 mg/ml.


The purity of this protein is >95% pure by SDS-PAGE

Alternate Names for GMF-beta Recombinant Protein

  • glia maturation factor beta
  • glia maturation factor, beta
  • GMF
  • GMFB
  • GMFbeta
  • GMF-beta


Glia Maturation Factor-Beta (GMF-Beta) is a 17 kDa protein nerve growth factor identified as a growth and differentiation factor in the vertebrate brain.Glia Maturation Factor-Beta stimulates differentiation of normal neurons as well as glial cells. GMFB inhibits the proliferation of the N-18 neuroblastoma line and the C6 glioma line while promoting their phenotypic expression.GMF-beta enhances the phenotypic expression of glia & neurons thus inhibits the proliferation of their respective tumors when added to cell culture. Cell- surface GMF-Beta acts on the target cells at close range when cells are in direct contact. GMF-Beta is produced by thymic epithelial cells and plays an important role in T cell development in favor of CD4+ T cells.GMF-Beta is a brain-specific protein which belongs to the actin-binding proteins (ADF) family. GMF-beta appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto-immune diseases, possibly through its ability to induce the production and secretion of various pro-inflammatory cytokines.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Contact Information

Product PDFs


Gene Symbol GMFB

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