GM-CSFR alpha Antibody (MM0316-8W1) [CoraFluor™ 1]

CoraFluor™ 1, amine reactive (Catalog:7920) and CoraFluor™ 2, amine reactive (Catalog # 7950) are terbium-based probes that have been developed for use as TR-FRET donors. They emit wavelengths compatible with commonly used fluorescent acceptor dyes such as BODIPY® (or BDY) and Janelia Fluor® dyes, FITC (Catalog # 5440), TMR and Cyanine 5 (Catalog # 5436). CoraFluor™ fluorescence is brighter and more stable in biological media than existing TR-FRET donors, leading to enhanced sensitivity and improved data generation. CoraFluor™ 1 exhibits excitation upon exposure to a 337 nm UV laser.

• Reactivity: Hu
• Applications: WB, Flow, CyTOF-ready
• Clone: MM0316-8W1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

GM-CSFR alpha Antibody (MM0316-8W1) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Immunogen: Human recombinant GM-CSFR alpha (extracellular domain)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CSF2RA
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for GM-CSFR alpha Antibody (MM0316-8W1) [CoraFluor™ 1]

• CD116 antigen
• CD116
• CDw116
• colony stimulating factor 2 receptor alpha subunit
• colony stimulating factor 2 receptor, alpha, low-affinity(granulocyte-macrophage)
• CSF2R
• CSF2RA
• CSF2RAX
• CSF2RAY
• CSF2RX
• CSF2RY
• GM-CSF R alpha
• GM-CSF receptor alpha subunit
• GMCSFR alpha
• GMCSFR
• GM-CSFRa
• GM-CSF-R-alpha
• GMCSFR-alpha
• GMR
• GMR-alpha
• granulocyte-macrophage colony-stimulating factor receptor alpha chain
• granulocyte-macrophage colony-stimulating factor receptor subunit alpha
• MGC3848
• MGC4838

Background

GM-CSF Receptor alpha is encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CSF2RA