Glutathione Peroxidase 2/GPX2 Antibody (496010) [Janelia Fluor® 549]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: 496010
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 549

Glutathione Peroxidase 2/GPX2 Antibody (496010) [Janelia Fluor® 549] Summary

• Immunogen: E. coli-derived recombinant human Glutathione Peroxidase 2
  Gly41-Ile190
  Accession # P18283
• Specificity: Detects endogenous human, mouse and rat GPX2 in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: GPX2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Glutathione Peroxidase 2/GPX2 Antibody (496010) [Janelia Fluor® 549]

• EC 1.11.1
• EC 1.11.1.9
• gastrointestinal glutathione peroxidase 2
• Gastrointestinal glutathione peroxidase
• GIGPX
• GI-GPx
• glutathione peroxidase 2 (gastrointestinal)
• Glutathione Peroxidase 2
• Glutathione peroxidase-gastrointestinal
• Glutathione peroxidase-related protein 2
• GPRP
• GPRP-2
• GPX2
• GPx-2
• GPx-GI
• GSHPx-2
• GSHPX-GI

Background

Glutathione Peroxidase 2 is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPX2