Glutathione Peroxidase 2/GPX2 Antibody (496010) [FITC]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: 496010
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: FITC

Glutathione Peroxidase 2/GPX2 Antibody (496010) [FITC] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: E. coli-derived recombinant human Glutathione Peroxidase 2
  Gly41-Ile190
  Accession # P18283
• Specificity: Detects endogenous human, mouse and rat GPX2 in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: GPX2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product MAB5470. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for Glutathione Peroxidase 2/GPX2 Antibody (496010) [FITC]

• EC 1.11.1
• EC 1.11.1.9
• gastrointestinal glutathione peroxidase 2
• Gastrointestinal glutathione peroxidase
• GIGPX
• GI-GPx
• glutathione peroxidase 2 (gastrointestinal)
• Glutathione Peroxidase 2
• Glutathione peroxidase-gastrointestinal
• Glutathione peroxidase-related protein 2
• GPRP
• GPRP-2
• GPX2
• GPx-2
• GPx-GI
• GSHPx-2
• GSHPx-GI

Background

Glutathione Peroxidase 2 is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPX2