GITR Ligand/TNFSF18 Recombinant Protein Summary
An un-tagged recombinant protein corresponding to amino acids 72 to 199 of Human GITR Ligand/TNFSF18
Source: E. coli
Amino Acid Sequence: MQLETAKEPC MAKFGPLPSK WQMASSEPPC VNKVSDWKLE ILQNGLYLIY GQVAPNANYN DVAPFEVRLY KNKDMIQTLT NKSKIQNVGG TYELHVGDTI DLIFNSEHQV LKNNTYWGII LLANPQFIS
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Liquid. In 10mM sodium citrate (pH 3.5), 10% glycerol, 1mMDTT
The purity of this protein is > 90% by SDS-PAGE. Molecular weight is 14.6kDa (129aa), confirmed by MALDI-TOF
Alternate Names for GITR Ligand/TNFSF18 Recombinant Protein
- Activation-inducible TNF-related ligand
- GITRLglucocorticoid-induced TNFR-related protein ligand
- Glucocorticoid-induced TNF-related ligand
- hGITRLGITR ligand
- TL6AITR ligand
- tumor necrosis factor (ligand) superfamily, member 18
- tumor necrosis factor ligand superfamily member 18
TNFSF18, also known as GITRL, belongs to the tumor necrosis factor(TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It is Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. Recombinant human TNFSF18 protein was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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