WB: Approx. 48 kDa band observed in human brain (hippocampus and substantia nigra) lysates (calculated MW of 48.5 kDa band according to NP_002231.1). Use in IHC, ICC/IF reported in scientific literature (PMID: 28398344).
48 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publications using NB100-74575 in the following applications:
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for GIRK2 Antibody
G protein-activated inward rectifier potassium channel 2
Inward rectifier K(+) channel Kir3.2
inward rectifier potassium channel KIR3.2
KATP2human G protein coupled inward rectifier potassium channel 2 (hiGIRK2)10KCNJ7KIR3.2
Potassium channel, inwardly rectifying subfamily J member 6
potassium inwardly-rectifying channel, subfamily J, member 6
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.