GEM Antibody (4B12) - Azide and BSA Free

Sandwich ELISA: GEM Antibody (4B12) [H00002669-M01] - Detection limit for recombinant GST tagged GEM is approximately 0.3ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 4B12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

GEM Antibody (4B12) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: GEM (AAH22010, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MTLNNVTMRQGTVGMQPQQQRWSIPADGRHLMVQKEPHQYSHRNRHSATPEDHCRRSWSSDSTDSVISSESGNTYYRVVLIGEQGVGKSTLANIFAGVHD
• Specificity: GEM - GTP binding protein overexpressed in skeletal muscle
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: GEM
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for GEM Antibody (4B12) - Azide and BSA Free

• GTP binding protein overexpressed in skeletal muscle
• GTP-binding mitogen-induced T-cell protein
• GTP-binding protein GEM
• GTP-binding protein overexpressed in skeletal muscle
• kinase-inducible Ras-like protein
• KIRMGC26294
• RAS-like protein KIR

Background

The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GEM Antibody (H00002669-M01)(1)

Publication using H00002669-M01

• Masahiro M, Kazuyuki S, Akiyuki T et al. A light-induced small G-protein gem limits the circadian clock phase-shift magnitude by inhibiting voltage-dependent calcium channels. Cell Rep . 2022-05-24 [PMID: 35613591]

Bioinformatics

• Gene Symbol: GEM
• Entrez:
  • 2669(Human)
• OMIM:
  • 600164(Human)
• Uniprot:
  • AAH22010(Human)