Recombinant Human GDF-3 Protein Summary
Description |
Recombinant bioactive protein containing 114 amino acids for Human GDF-3 Source:E. coli Amino Acid Sequence:(Q9NR23) |
Preparation Method |
Determined to be >98% pure by SDS-PAGE |
Source |
E. coli |
Protein/Peptide Type |
Recombinant Protein |
Gene |
GDF3 |
Purity |
>98%, by SDS-PAGE |
Endotoxin Note |
<0.1 ng/ug |
Applications/Dilutions
Dilutions |
|
Theoretical MW |
13 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at -20 to -80C. Avoid freeze-thaw cycles. |
Buffer |
Sterile filtered and lyophilized with no additive |
Concentration |
Lyoph |
Purity |
>98%, by SDS-PAGE |
Reconstitution Instructions |
Reconstitute in dH2O to a concentration of 0.1 - 1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4C for 1 week or -20C for long-term storage. |
Alternate Names for Recombinant Human GDF-3 Protein
Background
GDF-3 is a member of the TGF-Beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-Beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type-2 diabetes. Recombinant human GDF-3 contains 114 amino acids polypeptide chains
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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