GDAP1 Antibody - BSA Free

Immunohistochemistry: GDAP1 Antibody - BSA Free [NBP3-46247] - Immunohistochemistry of paraffin-embedded rat heart using (GDAP1 antibody) at dilution of 1:100

Western Blot: GDAP1 Antibody - BSA Free [NBP3-46247] - Mouse brain tissue were subjected to SDS PAGE followed by western blot with (GDAP1 Antibody) at dilution of 1:1000

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

GDAP1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit GDAP1 Antibody - BSA Free (NBP3-46247) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: ganglioside-induced differentiation-associated protein 1. (Uniprot# Q8TB36)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GDAP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:50 - 1:200
  • Western Blot 1:500 - 1:2000
• Theoretical MW: 38 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for GDAP1 Antibody - BSA Free

• Charcot-Marie-Tooth neuropathy 4A
• CMT2K
• CMT4
• CMT4A
• CMTRIA
• ganglioside differentiation associated protein 1
• ganglioside-induced differentiation-associated protein 1
• truncated ganglioside differentiation associated protein 1

Background

The GDAP1 gene encodes for a member of the ganglioside-induced differentiation-associated protein family that is active in signal transduction pathways during neuronal development. These proteins also monitor the mitochondrial network by endorsing mitochondrial fission. Isoform 1 is 358 amino acids long at 41 kDA while isoform 2 is 290 amino acids long at approximately 33 kDA. Neuropathy, muscular dystrophy, and multiple forms of Charcot-Marie-Tooth Disease have been linked to mutations in the GDAP1 gene. The GDAP1 gene is involved in NgR-p75(NTR)-Mediated signaling and interacts with genes such as FIS1, ATP6V1D, TUBB, UBC, and YWHAB.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GDAP1