Gastrin-releasing Peptide R/GRPR Antibody - BSA Free

Immunohistochemistry-Paraffin: Gastrin-releasing Peptide/Bombesin/Neuromedin C Antibody [NLS831] - Analysis of anti-GRPR antibody with human colon.

• Reactivity: Hu, Mu, Rt, Po, Bt, Bv, Ca, Ha, Pm, Pm, Rb
• Applications: IHC, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Gastrin-releasing Peptide R/GRPR Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human Gastrin-releasing Peptide R/GRPR.
• Epitope: 3rd cytoplasmic domain
• Specificity: Human GRPR. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ADAM28 (41%).
• Predicted Species: Rabbit (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GRPR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry 1:10 - 1:500
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 15-20 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Equine (88%), Turkey (82%), Chicken (82%), Lizard (82%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Gastrin-releasing Peptide R/GRPR Antibody - BSA Free

• Gastrin-releasing Peptide R
• gastrin-releasing peptide receptor
• Gastrinreleasing PeptideR
• Gastrin-releasing PeptideR
• GRP-preferring bombesin receptor
• GRPR
• GRP-R

Background

Gastrin-releasing peptide receptor (GRPR) is a Bombesin Receptor. In addition to its involvement in autism and mental retardation, GRPR may also play a role in the progression of cancer. Nicotine exposure induces an increase in GRPR expression in the lung Shriver et al. (2000). GRPR has been reported in brain, breast, colon, lung, lymph node, ovary, placenta, prostate, stomach, and uterus. It has also been shown to be expressed in several cancers, including those in breast, colon, lung, ovary, pancreas, and prostate.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRPR
• Entrez:
  • NM_005314(Human)
• Uniprot:
  • P30550(Human)