Species: Hu, Po, Bt, Ca, Eq, Pm, Pm, Rb, Bv
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Po, Bt, Bv, Ca, Ha, Pm, Pm, Rb
Applications: IHC, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Description
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq]
Bioinformatics
| Product By Gene ID |
2925 |
| Alternate Names |
- Gastrin-releasing Peptide R
- gastrin-releasing peptide receptor
- Gastrinreleasing PeptideR
- Gastrin-releasing PeptideR
- GRP-preferring bombesin receptor
- GRPR
- GRP-R
|
Research Areas for Gastrin-releasing Peptide R/GRPR
Find related products by research area and learn more about each of the different research areas below.
GPCR
