Recombinant Human Galectin-1 Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
Lyoph

Order Details

Recombinant Human Galectin-1 Protein Summary

Description
Recombinant bioactive protein for Human Galectin-1

Source:E. coli
Amino Acid Sequence:(P09382)

Preparation
Method
Determined to be >98% pure by SDS-PAGE
Details of Functionality
Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 ug/ml with a peak response obtained at 250 ug/ml.
Source
E. coli
Protein/Peptide Type
Biologically Active Protein
Gene
LGALS1
Purity
>95%, by SDS-PAGE
Endotoxin Note
<0.1 ng/ug

Applications/Dilutions

Theoretical MW
14.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
Sterile filtered and lyophilized from 20 mM Tris, pH 7.5.
Concentration
Lyoph
Purity
>95%, by SDS-PAGE
Reconstitution Instructions
Reconstitute in H2O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4C for 1 week or -20for future use.

Alternate Names for Recombinant Human Galectin-1 Protein

  • 14 kDa laminin-binding protein
  • 14 kDa lectin
  • Beta-galactoside-binding lectin L-14-I
  • BHL
  • DKFZp686E23103
  • GAL1
  • gal-1
  • Galaptin
  • galectin 1
  • Galectin1
  • Galectin-1
  • GBP
  • HBL
  • HLBP14
  • HPL
  • L-14
  • Lactose-binding lectin 1
  • Lectin galactoside-binding soluble 1
  • lectin, galactoside-binding, soluble, 1
  • LGALS1
  • Putative MAPK-activating protein PM12
  • S-Lac lectin 1

Background

Galectin-1 belongs to growing family of evolutionary conserved animal lectins. Galectins consists of Beta -galactoside binding lectins that contain homologous carbohydrate recognition domains (CRDs). Galectin-1 has the ability to induce apoptosis of activated T-cells and T-leukaemia cell lines. Other activities include cell differentiation and inhibition activity of CD45 protein phosphatase activity. Galectin also binds Beta -galactoside as well as CD45, CD3 and CD4. Recombinant Human Galectin is a 14.5 kDa protein consisting of 134 amino acid residues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

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Bioinformatics

Gene Symbol LGALS1
Entrez