Galanin R1/GALR1 Antibody - BSA Free

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Immunohistochemistry-Paraffin: Galanin R1/GALR1 Antibody [NLS4013] - Analysis of anti-GALR1 antibody with human brain.

Product Details

Summary
Reactivity Hu, Pm, Pm, Pm-OrSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

Order Details

Galanin R1/GALR1 Antibody - BSA Free Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 20 amino acid peptide from C-terminus of human Galanin R1/GALR1.
Epitope
C-terminal domain of human
Specificity
Human GALR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Orangutan (95%), Chimpanzee (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GALR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 7 ug/ml
Application Notes
.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (95%), Monkey (89%).

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Galanin R1/GALR1 Antibody - BSA Free

  • GAL1
  • Galanin R1
  • galanin receptor 1
  • galanin receptor type 1
  • GalaninR1
  • GALNR1
  • GALNRGALNR1GAL1-R
  • GALR1
  • GALR-1

Background

GalR1 is a Galanin Receptor that mediates the effects of the peptide galanin in a wide variety of tissues. Unlike GalR2, the primary signaling mechanism of GalR1 is by inhibiting adenylate cyclase through Gi. GalR1 regulates the GnRH neuroendocrine axis with its expression in POMC neurons. Pathogens like E. coli can cause diarrhea by increasing expression of Galanin Receptor 1 in the epithelial cells lining the colon, resulting in increased secretion of colonocyte chloride and fluid. GalR1 has been reported in brain, spinal cord, small intestine, colon, and eye. ESTs have been isolated from nerve and fetal lung/testis/B-cell libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GALR1
Entrez