GABA-B R1 [p Ser923] Antibody

Images

 
Western Blot: GABA-B R1 [p Ser923] Antibody [NB100-61102] - Western Blot: GABA-B R1 [p Ser923] Antibody [NB100-61102] - Rat synaptic membrane showing specific immune labeling of the ~102k GABA-B R1 [pt Ser923[ ...read more

Product Details

Summary
Reactivity Mu, Rt, Hu, Bv, PmSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

GABA-B R1 [p Ser923] Antibody Summary

Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser923 conjugated to KLH. Accession # Q9Z0U4
Modification
p Ser923
Specificity
Specific for endogenous levels of the ~102 kDa GABA-B R1 phosphorylated at Ser923. Immunolabeling is completely eliminated by treatment with lambda-phosphatase.
Predicted Species
Human (100%), Primate (100%), Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GABBR1
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
Theoretical MW
102 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Purity
Antigen Affinity-purified

Alternate Names for GABA-B R1 [p Ser923] Antibody

  • FLJ92613
  • GABA B R1
  • GABABR1
  • GABBR1
  • GABBR1-3
  • gamma-aminobutyric acid (GABA) B receptor, 1
  • gamma-aminobutyric acid type B receptor subunit 1
  • Gb1
  • GPRC3A
  • GPRC3Asubunit 1c
  • hGB1a
  • seven transmembrane helix receptor

Background

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling (Couve et al., 2004). Phosphorylation of Ser923 is thought to be important in the regulation of GABAB receptor function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for GABA-B R1 Antibody (NB100-61102) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GABBR1
Entrez
Uniprot