GABA-A R beta 1 Antibody

Images

 
Western Blot: GABA-A R beta 1 Antibody [NB300-197] - Mouse whole brain lysates showing specificimmunolabeling of the ~55 kDa beta1-subunit of the GABAA-R.
Western Blot: GABA-A R beta 1 Antibody [NB300-197] - Rat cerebellar (Cb) and hippocampal (Hipp) lysates showing specific immunolabeling of the ~55k beta 1-subunit of the GABA-A R beta 1 Antibody.

Product Details

Summary
Reactivity Mu, Rt, Hu, Bv, Ca, Ch, Pm, Xp, ZeSpecies Glossary
Applications WB, IHC, IHC-Fr, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.15 mg/ml

Order Details

GABA-A R beta 1 Antibody Summary

Immunogen
Fusion protein from the cytoplasmic loop of the beta1-subunit of rat GABA-A, Receptor, Beta 1 subunit.
Localization
Integral membrane protein
Specificity
Specific for the ~55 kDa beta 1-subunit of the GABA A receptor in Western blots.
Predicted Species
Human (100%), Chicken (100%), Canine (100%), Bovine (100%), Xenopus (100%), Zebrafish (100%), Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GABRB1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This antibody is useful in Immunohistochemistry (PMID: 21628464). Use in Immunohistochemistry-Frozen reported in scientific literature (PMID 21628464)
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NB300-197 in the following applications:

Reactivity Notes

It is anticipated that the antibody will react with bovine, canine, chicken, human, mouse, non-human primate, Xenopus, and zebra fish based on the fact that these species have 100% homology with the amino acid sequence used as antigen.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Concentration
0.15 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GABA-A R beta 1 Antibody

  • GABA A R beta 1
  • GABA(A) receptor subunit beta-1
  • GABAAR beta 1
  • GABAARb1
  • GABRB1
  • gamma-aminobutyric acid (GABA) A receptor, beta 1
  • gamma-aminobutyric acid receptor subunit beta-1

Background

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for GABA-A R beta 1 Antibody (NB300-197)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC-Fr.


Filter By Application
IHC-Fr
(1)
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Filter By Species
Mouse
(1)
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Bioinformatics

Gene Symbol GABRB1
Entrez
Uniprot