FSHR Antibody

Product Discontinued

FSHR Antibody Summary

• Immunogen: Synthetic 17 amino acid peptide from N-terminal extracellular domain of human FSHR.
• Specificity: Human FSHR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Porcine (94%), Guinea Pig (94%), Rabbit (94%), Canine (94%), Bat (94%), Primate (94%), Equine (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FSHR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10-20 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (100%), Gibbon (94%), Bovine (88%), Feline (88%), Goat (88%), Mouse (82%), Rat (82%), Sheep (82%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for FSHR Antibody

• follicle stimulating hormone receptor
• follicle-stimulating hormone receptor
• Follitropin receptor
• FSH R
• FSH receptor
• FSHR
• FSH-R
• LGR1
• LGR1FSHRO
• MGC141667
• MGC141668
• ODG1

Background

FSHR, a Glycoprotein Hormone Receptor, is required for normal ovarian development and follicle maturation in females. When activated, it stimulates ovarian follicular growth and production of estrogens, initiating a normal menstrual cycle. In males, FSHR is required for the initiation of spermatogenesis and normal sperm production. Two isoforms are produced by alternative splicing. FSHR expression has been reported in ovary, uterus, and testis. ESTs have been isolated from testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for FSHR Antibody (NLS2231)(2)

Publications using NLS2231

• Czogalla B, Partenheimer A, Badmann S et al. Nuclear Enolase-1/ MBP-1 expression and its association with the Wnt signaling in epithelial ovarian cancer Transl Oncol 2020-10-14 [PMID: 33069100] (IHC-P, Human)
• Deuster E, Mayr D, Hester A et al. Correlation of the Aryl Hydrocarbon Receptor with FSHR in Ovarian Cancer Patients Int J Mol Sci 2019-06-12 [PMID: 31212758] (IF/IHC, Human)

Bioinformatics

• Gene Symbol: FSHR
• Entrez:
  • 2492(Human)
• Uniprot:
  • P23945(Human)