Frizzled-9 Antibody (291004)

• Reactivity: Mu
• Applications: WB
• Clone: 291004
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Concentration: LYOPH

Frizzled-9 Antibody (291004) Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Frizzled‑9
  Ala23-Asp186 (predicted)
  Accession # Q9R216
• Specificity: Detects mouse Frizzled-9 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse (rm) Frizzled-1, -2, -3, -4, -6, -7, -8, rmFRP, or recombinant human Frizzled-5 is observed.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: FZD9
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Frizzled-9 Antibody (291004)

• CD349 antigen
• CD349
• frizzled (Drosophila) homolog 9
• frizzled homolog 9 (Drosophila)
• Frizzled9
• Frizzled-9
• fz-9
• FZD3fzE6
• FZD9
• FzE6
• hFz9

Background

Frizzled-9 belongs to the Frizzled family of seven-transmembrane receptors, which are signaling receptors for the family of secreted Wnt ligands. The amino-terminal extracellular cysteine-rich domains of human and mouse Frizzled-9 share 94% amino acid sequence homology.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Frizzled-9 Antibody (MAB2440)(1)

Publication using MAB2440

• Tsai H, Deng W, Lai W, Chiu W, Yang C, Tsai Y, Hwang S, Renshaw P Wnts enhance neurotrophin-induced neuronal differentiation in adult bone-marrow-derived mesenchymal stem cells via canonical and noncanonical signaling pathways. PLoS ONE, 2014-08-29;9(8):e104937. 2014-08-29 [PMID: 25170755] (Functional Assay, Human)

Bioinformatics

• Gene Symbol: FZD9
• Uniprot:
  • Q9R216()