Frizzled-8 Antibody

Immunohistochemistry-Paraffin: Frizzled-8 Antibody [NLS4766] - Anti-FZD8 / Frizzled 8 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry: Frizzled-8 Antibody [NLS4766] - Analysis of anti-FZD8 / Frizzled 8 antibody with pancreas, Islet of Langerhans at 30 ug/ ml.

Immunohistochemistry-Paraffin: Frizzled-8 Antibody [NLS4766] - Analysis of anti-FZD8 / Frizzled 8 antibody with human lung, non-small cell carcinoma.

Immunohistochemistry-Paraffin: Frizzled-8 Antibody [NLS4766] - Anti-FZD8 / Frizzled 8 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Discontinued

Frizzled-8 Antibody Summary

• Immunogen: Synthetic 15 amino acid peptide from N-terminal extracellular domain of human FZD8 / Frizzled 8.
• Epitope: N-terminal extracellular domain of human
• Specificity: Human Frizzled-8. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Opossum (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FZD8
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 30 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Marmoset (100%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Frizzled-8 Antibody

• frizzled (Drosophila) homolog 8
• frizzled 8
• frizzled family receptor 8
• frizzled homolog 8 (Drosophila)
• Frizzled8
• Frizzled-8
• FZ-8
• FZD8
• hFZ8

Background

FZD8 is a Frizzled Receptor that mediates Wnt signaling and is involved in determining vertebrate axis and tissue polarity. FZD8 is expressed during embryonic development in forming and differentiating somites in mice. FZD8 expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FZD8
• Entrez:
  • 8325(Human)