FoxP2 Antibody (5C11A2)

Western Blot: FoxP2 Antibody (5C11A2) [NBP2-37558] - Western blot analysis using FOXP2 mAb against human FOXP2 (AA: 47-287) recombinant protein. (Expected MW is 52.8 kDa)

ELISA: FoxP2 Antibody (5C11A2) [NBP2-37558] - Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);

Product Discontinued

FoxP2 Antibody (5C11A2) Summary

• Immunogen: Purified recombinant fragment of human MAPK3 expressed in E. Coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FOXP2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Western Blot 1:500 - 1:2000
• Theoretical MW: 85 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: 0.03% Sodium Azide
• Purity: Unpurified

Alternate Names for FoxP2 Antibody (5C11A2)

• CAG repeat protein 44
• CAGH44
• CAGH44TNRC10forkhead box protein P2
• DKFZp686H1726
• forkhead box P2
• forkhead/winged-helix transcription factor
• FoxP2
• SPCH1
• TNRC10
• trinucleotide repeat containing 10
• Trinucleotide repeat-containing gene 10 protein

Background

FOXP2 encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FOXP2