FOXL2 Antibody (1019104) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: IHC, ICC/IF
• Clone: 1019104
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

FOXL2 Antibody (1019104) [Alexa Fluor® 647] Summary

• Immunogen: Synthetic peptide containing human FOXL2
  Accession # P58012
• Specificity: Detects human FOXL2 in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FOXL2 Antibody (1019104) [Alexa Fluor® 647]

• BPES
• BPES1
• BPES1PINTO
• forkhead box L2
• forkhead box protein L2
• forkhead transcription factor FOXL2
• FOXL2
• PFRK
• PINTO
• POF3

Background

FOXL2 is a forkhead transcription factor which plays a role in ovarian development and function. It is transcribed very early in somatic cells of the developing gonad (before sex determination) and its expression persists in the follicular cells of the adult ovary. Females missing the FOXL2 gene appear to be male.  FOXL2 prevents transdifferentiation of an adult ovary to a testis.  Overexpression of FOXL2 has been implicated in endometriosis with 3-fold higher mRNA expression in endometriosis than in healthy endometrium.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.